Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491057 | 0.92 | KDM4E (0.70) | KDM4EALDH1A1PKMPOLBGAA | |
| SCHEMBL1491083 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1PKMPOLBGAA | |
| SCHEMBL12340306 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1PKMPOLBGAA | |
| SCHEMBL1491118 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1PKMPOLBSLC2A1 | |
| SCHEMBL1491110 | 0.90 | KDM4E (1.00) | KDM4EALDH1A1PKMTSHRP2RX7 | |
| SCHEMBL568868 | 0.90 | KDM4E (0.72) | KDM4EALDH1A1PKMPOLBGAA | |
| SCHEMBL1491139 | 0.87 | KDM4E (0.64) | KDM4EALDH1A1PKMPOLBTSHR | |
| SCHEMBL1613253 | 0.86 | KDM4E (0.62) | KDM4EALDH1A1PKMPOLBGAA | |
| SCHEMBL1491055 | 0.86 | KDM4E (0.62) | KDM4EALDH1A1PKMPOLBGAA | |
| SCHEMBL174384 | 0.86 | KDM4E (0.62) | KDM4EALDH1A1PKMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716257-B2 | OXIDATION DYES, WHICH ARE USED FOR TREATMENT OF HUMAN HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | disclosed |
| EP-1236460-B1 | Bridged diamino pyrazoles and colouring agents containing them | WELLA AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-11-21 | — | — | US | disclosed |
| EP-1236460-A1 | Bridged diamino pyrazoles and colouring agents containing them | Wella Aktiengesellschaft (DE) | 2002-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | ALK, DDC, CBR1 | KDM4E 1827/4885ALDH1A1 11/4885PKM 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.