Phenol

Phenol

SCHEMBL6760455

C=C(C)C(=O)O.CC1CO1.Oc1ccccc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
GLA P06280 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA9 Q16790 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA14 Q9ULX7 1/20 0.39
PKM P14618 1/20 0.35
MAPK1 P28482 1/20 0.35
CES2 O00748 1/20 0.34
HPGD P15428 2/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 1/20 0.33
NOTUM Q6P988 1/20 0.33
KIF11 P52732 1/20 0.33
DEGS1 O15121 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL27566674 0.87 TDP1 (0.48) ALDH1A1CA12CA1CA2GLA
Methacrylic Acid SCHEMBL4631005 0.87 ALDH1A1 (0.39) ALDH1A1KDM4ETDP1PKMMAPK1
Methacrylic Acid SCHEMBL2913483 0.87 ALDH1A1 (0.39) ALDH1A1KDM4ETDP1PKMMAPK1
Phenol SCHEMBL1224881 0.84 CA12 (0.55) ALDH1A1CA12CA1CA2GLA
Phenol SCHEMBL174433 0.84 CA12 (0.55) ALDH1A1KDM4ECA12CA1CA2
Phenol SCHEMBL184346 0.84 CA12 (0.55) ALDH1A1KDM4ECA12CA1CA2
Phenol SCHEMBL9052733 0.84 CA12 (0.55) ALDH1A1KDM4ECA12CA1CA2
Phenol SCHEMBL1738526 0.84 CA12 (0.55) ALDH1A1CA12CA1CA2GLA
Phenol SCHEMBL1199743 0.84 CA12 (0.55) ALDH1A1KDM4ECA12CA1CA2
Phenol SCHEMBL165006 0.84 CA12 (0.55) ALDH1A1KDM4ECA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
US-20040198880-A1 Floor polish composition JOHNSONDIVERSEY, INC. 2004-10-07 US disclosed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO disclosed