Sugi Predict

Sugi Predict / Compounds / SCHEMBL6760577

SCHEMBL6760577

SCHEMBL6760577

CCn1cnc2cc(F)ccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 11/20 0.51
▸ RAB9A P51151 10/20 0.51
▸ KMT2A Q03164 5/20 0.51
▸ MEN1 O00255 3/20 0.51
▸ GAA P10253 3/20 0.51
▸ KDM4E B2RXH2 7/20 0.50
▸ MAPT P10636 6/20 0.50
▸ ALDH1A1 P00352 5/20 0.50
▸ SMN1; SMN2 Q16637 5/20 0.50
▸ HSD17B10 Q99714 3/20 0.50
▸ HPGD P15428 1/20 0.50
▸ HDAC1 Q13547 1/20 0.48
▸ HDAC8 Q9BY41 1/20 0.48
▸ TP53 P04637 3/20 0.47
▸ HTT P42858 2/20 0.47
▸ POLB P06746 2/20 0.47
▸ LMNA P02545 1/20 0.47
▸ GFER P55789 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ PRPS1 P60891 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8508794 0.92 NPC1 (0.46) NPC1RAB9AKMT2AMEN1GAA
SCHEMBL11682446 0.86 NPC1 (0.51) NPC1RAB9AGAAKDM4EMAPT
SCHEMBL17067027 0.86 NPC1 (0.41) NPC1RAB9AKMT2AMEN1GAA
SCHEMBL19848180 0.83 LMNA (0.60) NPC1RAB9AGAAKDM4EMAPT
SCHEMBL21991220 0.83 PRPS1 (0.43) NPC1RAB9AKMT2AMEN1GAA
SCHEMBL31202960 0.83 PRPS1 (0.43) NPC1RAB9AKMT2AMEN1GAA
SCHEMBL19911431 0.82 PRPS1 (0.44) NPC1RAB9AMAPTSMN1; SMN2HSD17B10
SCHEMBL8510302 0.82 GRM5 (0.46) NPC1RAB9AKMT2AMEN1GAA
SCHEMBL19848702 0.81 MEN1 (0.42) NPC1RAB9AKMT2AMEN1GAA
SCHEMBL29340889 0.81 POLB (0.59) MAPTHSD17B10POLBPRPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 — — EP claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 — — US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 — — EP claimed
US-12421218-B2 Substituted pyrazine-carboxamide derivatives BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-09-23 — — US disclosed
US-20240417394-A1 NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES BOEHRINGER INGELHEIM INT (DE) 2024-12-19 — — US disclosed
US-20240182453-A1 NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2024-06-06 — — US disclosed
US-20240174652-A1 NOVEL DIOXANE DERIVATIVES BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2024-05-30 — — US disclosed
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-08-25 — — US disclosed
EP-3467930-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-04-10 — — EP disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 — — US disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 — — US disclosed
US-4018610-A Supersensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1977-04-19 — — US disclosed
US-4010037-A Spectrally sensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1977-03-01 — — US disclosed
US-4002480-A CONTAINING A DINUCLEAR MEROCYANINE SENSITIZING DYE AND AN ANTIFOGGING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1977-01-11 — — US disclosed
US-3994733-A CYANINE DYES, A BENZOTHIAZOLE, OR BENZOTHIAZOLONE, OR NAPHTHOTHIAZOLE, OR NAPHTHOTHIAZOLONE, OR A QUINOLONE FUJI PHOTO FILM CO., LTD. (JA) 1976-11-30 — — US disclosed
US-3977883-A Spectrally sensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 — — US disclosed
US-3967967-A CYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-07-06 — — US disclosed
US-3966477-A Spectrally sensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-06-29 — — US disclosed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 — — US disclosed
US-3951666-A CYANINE AND MEROCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421218-B2 Substituted pyrazine-carboxamide derivatives GRM4, GRIA4, GRM1 NPC1 1174/4885RAB9A 2587/4885KMT2A 1577/4885
US-20240174652-A1 NOVEL DIOXANE DERIVATIVES GRM4, GRIA4, GRIK4 NPC1 753/4885RAB9A 1775/4885KMT2A 1879/4885
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery BPTF, BRD4, KCNN2 NPC1 2529/4885RAB9A 3611/4885KMT2A 458/4885
US-20240417394-A1 NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES GRIA4, GRM4, GRM1 NPC1 1467/4885RAB9A 2453/4885KMT2A 1367/4885
US-20240182453-A1 NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES GRIA4, GRM4, GRM1 NPC1 1467/4885RAB9A 2453/4885KMT2A 1367/4885
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery BPTF, BRD4, KCNN2 NPC1 2529/4885RAB9A 3611/4885KMT2A 458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.