Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 8/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760738 | 0.94 | SOAT1 (0.78) | SOAT1ALDH1A1CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL6279700 | 0.90 | SOAT1 (0.84) | SOAT1ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL4836774 | 0.89 | SOAT1 (0.77) | SOAT1ALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL960484 | 0.89 | SOAT1 (1.00) | SOAT1ALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL29845569 | 0.89 | SOAT1 (1.00) | SOAT1ALDH1A1TSHRCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6283825 | 0.88 | SOAT1 (1.00) | SOAT1ALDH1A1TSHRCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL29972967 | 0.88 | SOAT1 (1.00) | SOAT1ALDH1A1TSHRCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL1704627 | 0.88 | SOAT1 (1.00) | SOAT1ALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL6279708 | 0.86 | SOAT1 (0.83) | SOAT1ALDH1A1TSHRUSP2NPC1 | |
| SCHEMBL4836791 | 0.84 | SOAT1 (0.76) | SOAT1ALDH1A1TSHRCYP2E1CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | KOWA COMPANY, LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | LCAT, ACAT2, ACAT1 | SOAT1 5/4885ALDH1A1 307/4885TSHR 3677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.