SCHEMBL6760795

SCHEMBL6760795

CCNc1n[c]nc(NCC)n1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
GAA P10253 3/20 0.45
CYP1A2 P05177 3/20 0.45
CYP2C19 P33261 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
POLB P06746 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MCL1 Q07820 1/20 0.42
HTT P42858 2/20 0.39
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.36
ALOX15 P16050 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11222546 0.84 LMNA (0.59) LMNAGAACYP1A2CYP2C19L3MBTL1
SCHEMBL6547123 0.84 LMNA (0.39) LMNAGAACYP1A2CYP2C19L3MBTL1
SCHEMBL1034033 0.80 LMNA (0.74) LMNAGAACYP1A2CYP2C19L3MBTL1
SCHEMBL10569070 0.80 GAA (0.43) LMNAGAACYP1A2CYP2C19L3MBTL1
Hydrochloric Acid SCHEMBL11741238 0.77 LMNA (0.70) LMNAGAACYP1A2CYP2C19L3MBTL1
SCHEMBL9118084 0.77 SLC29A1 (0.44) CYP1A2CYP2C19L3MBTL1KMT2AKDM4E
SCHEMBL6279465 0.75 KCNH3 (0.50) KMT2AHTTALDH1A1
SCHEMBL8465992 0.73 KMT2A (0.53) KMT2AHTT
SCHEMBL9731429 0.73 KCNH3 (0.46)
SCHEMBL8468561 0.72 KCNH3 (0.33) CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4758568-A Quinoline therapeutic agents PFIZER INC. (US) 1988-07-19 US claimed
US-6815152-B2 FOR USE AS CINEMATOGRAPHIC COLOR PHOTOGRAPHIC PHOTOSENSITIVE MATERIAL, IMAGE QUALITY, STORAGE STABILITY AND PROCESSING STABILITY FUJI PHOTO FILM. CO., LTD. (JP) 2004-11-09 US disclosed
US-20030203326-A1 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. 2003-10-30 US disclosed
EP-0385461-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1995-01-18 EP disclosed
US-5192738-A Heat sensitive elements for images FUJI PHOTO FILM CO., LTD. (JP) 1993-03-09 US disclosed
US-5063146-A SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-11-05 US disclosed
US-4968593-A OXONOL DYE, SINGLET OXYGEN QUENCHER FUJI PHOTO FILM CO., LTD. (JP) 1990-11-06 US disclosed
EP-0385461-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-09-05 EP disclosed