Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6766142 | 0.88 | LMNA (0.51) | HTTSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL6759424 | 0.86 | LMNA (0.52) | HTTSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL6562898 | 0.82 | KMT2A (0.45) | SMN1; SMN2TSHRALDH1A1SLC6A9RAB9A | |
| SCHEMBL1493676 | 0.81 | HTT (0.59) | HTTSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL6763723 | 0.78 | GRIA4 (0.53) | HTTLMNATSHRALDH1A1HPGD | |
| SCHEMBL6763747 | 0.77 | ALDH1A1 (0.47) | HTTSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL5725957 | 0.75 | NPC1 (0.58) | HTTSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL6765791 | 0.75 | PPARG (0.59) | LMNAALDH1A1HPGDKMT2A | |
| SCHEMBL6760992 | 0.75 | HTT (0.47) | HTTSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL29564150 | 0.74 | CA9 (0.49) | SMN1; SMN2LMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | DAVISON JOSHUA ZWICK (US) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | GRIN1, GRIN2A, GRIA1 | HTT 1694/4885SMN1; SMN2 386/4885LMNA 4868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.