SCHEMBL676103

SCHEMBL676103

COc1ccc2c3c(c4c(c2c1)OC(c1ccccc1)(c1ccc(N2CCOCC2)cc1)C=C4)C1(CC(C)(C)CC(C)(C)C1)c1ccccc1-3

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.34
TSHR P16473 3/20 0.34
HSD17B10 Q99714 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPK1 P28482 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
POLB P06746 1/20 0.34
ADAM17 P78536 1/20 0.32
ALDH1A1 P00352 5/20 0.32
KDM4E B2RXH2 5/20 0.32
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ATM Q13315 3/20 0.32
HTT P42858 3/20 0.32
MEN1 O00255 2/20 0.32
LMNA P02545 2/20 0.32
STK10 O94804 1/20 0.31
SLK Q9H2G2 1/20 0.31
HPGD P15428 2/20 0.31
RAB9A P51151 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20369879 1.00 MAPT (0.34) MAPTTSHRHSD17B10KMT2AMAPK1
SCHEMBL10102396 0.98 MAPT (0.33) MAPTTSHRHSD17B10KMT2AMAPK1
SCHEMBL12424707 0.97 MAPT (0.33) MAPTTSHRHSD17B10KMT2AMAPK1
SCHEMBL10106918 0.97 MAPT (0.34) MAPTTSHRHSD17B10KMT2AMAPK1
SCHEMBL10102279 0.94 MAPT (0.32) MAPTTSHRHSD17B10KMT2AALDH1A1
SCHEMBL13868746 0.93 RAB9A (0.33) MAPTKMT2AADAM17ALDH1A1KDM4E
SCHEMBL10102281 0.92 MAPT (0.31) MAPTTSHRHSD17B10KMT2AALDH1A1
SCHEMBL13868656 0.92 PRKDC (0.36) MAPTTSHRHSD17B10KMT2AMAPK1
SCHEMBL12205490 0.91 KDM4E (0.32) MAPTALDH1A1KDM4EHTTSTK10
SCHEMBL13868646 0.91 PRKDC (0.36) MAPTKMT2ASMN1; SMN2ADAM17ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240241291-A1 FUNCTIONAL LAMINATE AND FUNCTIONAL LENS COMPRISING THE FUNCTIONAL LAMINATE TOKUYAMA CORPORATION (JP) 2024-07-18 US disclosed
US-20240241291-A1 FUNCTIONAL LAMINATE AND FUNCTIONAL LENS COMPRISING THE FUNCTIONAL LAMINATE TOKUYAMA CORPORATION (JP) 2024-07-18 US disclosed
US-20230272252-A1 ADHESIVE COMPOSITION, LAMINATE AND OPTICAL ARTICLE COMPRISING THE LAMINATE TOKUYAMA CORPORATION (JP) 2023-08-31 US disclosed
US-20230272252-A1 ADHESIVE COMPOSITION, LAMINATE AND OPTICAL ARTICLE COMPRISING THE LAMINATE TOKUYAMA CORPORATION (JP) 2023-08-31 US disclosed
US-20230260669-A1 CURABLE COMPOSITION AND CURED BODY OF SAME TOKUYAMA CORPORATION (JP) 2023-08-17 US disclosed
US-20230260669-A1 CURABLE COMPOSITION AND CURED BODY OF SAME TOKUYAMA CORPORATION (JP) 2023-08-17 US disclosed
EP-3345954-B1 POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE TOKUYAMA CORP (JP) 2023-07-05 EP disclosed
EP-4183579-A1 CURABLE COMPOSITION AND CURED BODY OF SAME Tokuyama Corporation (JP) 2023-05-24 EP disclosed
US-11649327-B2 Photochromic curable composition, use thereof, and polyrotaxane monomers TOKUYAMA CORPORATION (JP) 2023-05-16 US disclosed
US-11649327-B2 Photochromic curable composition, use thereof, and polyrotaxane monomers TOKUYAMA CORPORATION (JP) 2023-05-16 US disclosed
US-8066917-B2 Photochromic curable composition TOKUYAMA CORPORATION (JP) 2011-11-29 US disclosed
US-8066917-B2 Photochromic curable composition TOKUYAMA CORPORATION (JP) 2011-11-29 US disclosed
EP-2377902-A1 COATING COMPOSITION, PROCESS FOR PRODUCTION OF THE COMPOSITION, AND LAMINATE WITH HARD COAT LAYER Tokuyama Corporation (JP) 2011-10-19 EP disclosed
US-20110244244-A1 COATING COMPOSITION, PROCESS FOR PRODUCING THE COMPOSITION, AND LAMINATE HAVING A HARD COAT LAYER TOKUYAMA CORPORATION (JP) 2011-10-06 US disclosed
US-20110244244-A1 COATING COMPOSITION, PROCESS FOR PRODUCING THE COMPOSITION, AND LAMINATE HAVING A HARD COAT LAYER TOKUYAMA CORPORATION (JP) 2011-10-06 US disclosed
US-20110062396-A1 CHROMENE COMPOUND TOKUYAMA CORPORATION (JP) 2011-03-17 US disclosed
US-20110062396-A1 CHROMENE COMPOUND TOKUYAMA CORPORATION (JP) 2011-03-17 US disclosed
EP-2275418-A1 CHROMENE COMPOUND Tokuyama Corporation (JP) 2011-01-19 EP disclosed
US-20100230650-A1 PHOTOCHROMIC CURABLE COMPOSITION GULFSTREAM INC. (CA) 2010-09-16 US disclosed
US-20100230650-A1 PHOTOCHROMIC CURABLE COMPOSITION GULFSTREAM INC. (CA) 2010-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110062396-A1 CHROMENE COMPOUND CDYL, NR0B1, NR1H2 MAPT 4740/4885TSHR 330/4885HSD17B10 401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.