Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763869 | 0.96 | ESR1 (0.44) | TSHRTP53CYP3A4MAPK1ESR1 | |
| SCHEMBL6762452 | 0.93 | TSHR (0.45) | TSHRTP53CYP3A4MAPK1ESR1 | |
| SCHEMBL6759839 | 0.93 | TSHR (0.45) | TSHRTP53CYP3A4MAPK1ESR1 | |
| SCHEMBL6766053 | 0.92 | ESR1 (0.46) | TSHRTP53CYP3A4MAPK1ESR1 | |
| SCHEMBL6762519 | 0.91 | ALDH1A1 (0.41) | TSHRESR1ALDH1A1KDM4E | |
| SCHEMBL6761346 | 0.91 | FFAR1 (0.44) | TSHRTP53CYP3A4MAPK1ESR1 | |
| SCHEMBL6763970 | 0.89 | FFAR1 (0.46) | TSHRESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6762901 | 0.89 | ESR1 (0.44) | TSHRTP53CYP3A4MAPK1ESR1 | |
| SCHEMBL6759787 | 0.88 | NR4A1 (0.45) | TSHRTP53CYP3A4MAPK1ESR1 | |
| SCHEMBL6763062 | 0.88 | ALDH1A1 (0.42) | TSHRCYP3A4ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | VALENZUELA CORTES CARMEN MARIA (CL) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | PDE3A, PDE3B, PDE12 | TSHR 4615/4885TP53 4869/4885CYP3A4 417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.