Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763869 | 0.93 | ESR1 (0.44) | ALDH1A1HSD17B10TSHRTDP1ESR1 | |
| SCHEMBL6761244 | 0.91 | TSHR (0.45) | ALDH1A1TSHRKDM4EESR1 | |
| SCHEMBL6763062 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHRTDP1HPGD | |
| SCHEMBL6761222 | 0.90 | NR4A1 (0.40) | ALDH1A1TSHRTDP1ESR1NR4A1 | |
| SCHEMBL6759787 | 0.89 | NR4A1 (0.45) | ALDH1A1TSHRESR1NR4A1 | |
| SCHEMBL6761389 | 0.88 | NR4A1 (0.46) | ALDH1A1TSHRESR1NR4A1 | |
| SCHEMBL6762243 | 0.87 | TDP1 (0.43) | ALDH1A1HSD17B10TSHRTDP1HPGD | |
| SCHEMBL6762250 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHRTDP1KDM4E | |
| SCHEMBL6762901 | 0.85 | ESR1 (0.44) | ALDH1A1HSD17B10TSHRTDP1ESR1 | |
| SCHEMBL6761346 | 0.84 | FFAR1 (0.44) | ALDH1A1TSHRTDP1ESR1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | VALENZUELA CORTES CARMEN MARIA (CL) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | PDE3A, PDE3B, PDE12 | ALDH1A1 1744/4885HSD17B10 192/4885TSHR 4615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.