Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | HNF4A | P41235 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761534 | 1.00 | LMNA (0.41) | LMNAMAPTPDE4DHNF4AGLA | |
| SCHEMBL6761266 | 0.90 | LMNA (0.39) | LMNAMAPTPDE4DHNF4AGLA | |
| SCHEMBL6760914 | 0.90 | LMNA (0.39) | LMNAMAPTPDE4DHNF4AGLA | |
| SCHEMBL6757319 | 0.89 | LMNA (0.37) | LMNAMAPTPDE4DHNF4AGLA | |
| SCHEMBL6757320 | 0.89 | LMNA (0.37) | LMNAMAPTPDE4DHNF4AGLA | |
| SCHEMBL6762173 | 0.88 | PARP1 (0.40) | KDM4EALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL6760921 | 0.86 | LMNA (0.36) | LMNAMAPTPDE4DHNF4AGLA | |
| SCHEMBL6760922 | 0.86 | LMNA (0.36) | LMNAMAPTPDE4DHNF4AGLA | |
| SCHEMBL6764350 | 0.84 | LMNA (0.36) | LMNAMAPTPDE4DGLAKDM4E | |
| SCHEMBL6764344 | 0.84 | LMNA (0.36) | LMNAMAPTPDE4DGLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106635-A1 | having small-conductance potassium channel (SK) blocking activity | TANABE SEIYAKU CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106635-A1 | having small-conductance potassium channel (SK) blocking activity | KCNN1, KCNN2, KCNN3 | LMNA 612/4885MAPT 4457/4885PDE4D 2101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.