Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 9/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647026 | 0.89 | PLA2G4B (0.41) | PLA2G2ABLMPLA2G4BPLA2G4A | |
| SCHEMBL6761751 | 0.88 | TP53 (0.45) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL3813554 | 0.86 | NR1H2 (0.41) | — | |
| SCHEMBL11649618 | 0.81 | PTPN1 (0.42) | — | |
| SCHEMBL3660817 | 0.80 | KEAP1 (0.49) | TSHR | |
| SCHEMBL11750518 | 0.80 | SMN1; SMN2 (0.41) | BLMTP53 | |
| SCHEMBL191548 | 0.79 | MAOB (0.50) | — | |
| SCHEMBL9972488 | 0.79 | PLA2G2A (0.74) | PLA2G2ABLMTP53TSHRPLA2G4B | |
| SCHEMBL6761753 | 0.78 | TP53 (0.47) | TP53TSHRPLA2G4BS1PR4S1PR1 | |
| SCHEMBL6494515 | 0.77 | S1PR4 (0.49) | TP53TSHRPLA2G4BS1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720424-B1 | VEGF (VASCULAR ENDOTHELIAL GROWTH FACTOR) RECEPTOR ANTAGONISTS AND ANGIOGENESIS INHIBITORS SUPPRESS VASCULAR HYPERPERMEABILITY; PHENYLALKYLCARBONYL SUBSTITUENT ON THE AMINO | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-04-13 | — | — | US | disclosed |
| EP-1193246-A1 | AMINOBENZOIC ACID DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-04-03 | — | — | EP | disclosed |