SCHEMBL676205

SCHEMBL676205

C#Cc1c(Cl)cnc(OC)c1C(=O)c1c(C)cc(OC)c(OC)c1OC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.33
SCN9A Q15858 2/20 0.33
MEN1 O00255 2/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
CHEK1 O14757 1/20 0.32
IKBKB O14920 1/20 0.32
AURKA O14965 1/20 0.32
DCLK1 O15075 1/20 0.32
RPS6KA5 O75582 1/20 0.32
PRKD3 O94806 1/20 0.32
MAP4K4 O95819 1/20 0.32
RET P07949 1/20 0.32
PHKG2 P15735 1/20 0.32
CDK2 P24941 1/20 0.32
FLT4 P35916 1/20 0.32
MAPKAPK2 P49137 1/20 0.32
CLK2 P49760 1/20 0.32
GSK3B P49841 1/20 0.32
IRAK1 P51617 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674954 0.87 ALDH1A1 (0.36) KMT2ASCN9AMEN1LMNAMAPT
SCHEMBL29351890 0.85 HPGD (0.35) KMT2ASCN9AMEN1LMNAMAPT
SCHEMBL322562 0.85 HPGD (0.35) KMT2ASCN9AMEN1LMNAMAPT
SCHEMBL29814930 0.85 HPGD (0.35) KMT2ASCN9AMEN1LMNAMAPT
SCHEMBL676223 0.85 ALDH1A1 (0.35) KMT2ASCN9AMEN1LMNAMAPT
SCHEMBL5942445 0.84 LMNA (0.33) SCN9ALMNACHEK1IKBKBAURKA
SCHEMBL675072 0.83 PTPN1 (0.39) KMT2ASCN9AMEN1LMNAMAPT
SCHEMBL676192 0.81 LMNA (0.34) KMT2AMEN1LMNAMAPTCHEK1
SCHEMBL676458 0.81 KMT2A (0.34) KMT2ASCN9AMEN1LMNAMAPT
SCHEMBL676832 0.81 PDE4D (0.37) SCN9APTGS2ALOX12MAPK10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10136643-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2018-11-27 US claimed
US-20160353737-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2016-12-08 US claimed
US-9474281-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2016-10-25 US claimed
US-20150164084-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2015-06-18 US claimed
US-8962661-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2015-02-24 US claimed
EP-2323487-A2 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-05-25 EP claimed
US-20110104307-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-05-05 US claimed
WO-2010002026-A2 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-01-07 WO claimed
EP-2036436-A1 ANTIBACTERIAL COMPOSITION AND METHOD FOR CONTROL OF PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-03-18 EP claimed
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-08-31 US claimed
EP-1679003-A1 BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-07-12 EP claimed
US-20060089390-A1 3-benzoyl-2,4,5-substituted pyridine derivatives or salts thereof and bactericides containing the same ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-04-27 US claimed
EP-1559320-A1 3-BENZOYL-2,4,5-SUBSTITUTED PYRIDINE DERIVATIVES OR SALTS THEREOF AND BACTERICIDES CONTAINING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 2005-08-03 EP claimed
US-10136643-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2018-11-27 US disclosed
US-20170188579-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA (JP) 2017-07-06 US disclosed
US-9655362-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2017-05-23 US disclosed
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-08-31 US disclosed
EP-1679003-A1 BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-07-12 EP disclosed
US-20060089390-A1 3-benzoyl-2,4,5-substituted pyridine derivatives or salts thereof and bactericides containing the same ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-04-27 US disclosed
EP-1559320-A1 3-BENZOYL-2,4,5-SUBSTITUTED PYRIDINE DERIVATIVES OR SALTS THEREOF AND BACTERICIDES CONTAINING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160353737-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES AFF4, HCN4, CNPY2 KMT2A 2769/4885SCN9A 277/4885MEN1 2846/4885
US-20150164084-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES AFF4, HCN4, CNPY2 KMT2A 2769/4885SCN9A 277/4885MEN1 2846/4885
US-10136643-B2 Fungicidal composition and method for controlling plant diseases AFF4, HCN4, CNPY2 KMT2A 2769/4885SCN9A 277/4885MEN1 2846/4885
US-20110104307-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES AFF4, HCN4, CNPY2 KMT2A 2769/4885SCN9A 277/4885MEN1 2846/4885
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases CBR3, CNPY2, PAH KMT2A 2575/4885SCN9A 266/4885MEN1 3219/4885
US-20170188579-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES CBR3, CNPY2, PAH KMT2A 2575/4885SCN9A 266/4885MEN1 3219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.