Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762193 | 1.00 | CTSK (0.46) | CTSKNPC1RAB9ALMNATP53 | |
| SCHEMBL6760302 | 0.88 | MAPT (0.49) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL6760301 | 0.88 | MAPT (0.49) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL6755720 | 0.85 | RAB9A (0.53) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL6755717 | 0.85 | RAB9A (0.53) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL6652881 | 0.83 | MAPT (0.52) | LMNATP53SMN1; SMN2HDAC3HDAC8 | |
| SCHEMBL6652883 | 0.83 | MAPT (0.52) | LMNATP53SMN1; SMN2HDAC3HDAC8 | |
| SCHEMBL6683480 | 0.80 | CA1 (0.46) | LMNASMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL6683479 | 0.80 | CA1 (0.46) | LMNASMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL21378571 | 0.79 | HDAC3 (0.43) | CTSKNPC1RAB9ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716878-B1 | BACTERICIDE, ANTIPROTOZOAL; VANCOMYCIN RESISTANT ENTEROCOCCI AND BETA-LACTAM ANTIBIOTIC-RESISTANT BACTERIA, METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; HYDROXAMIC ACID AND N-FORMYL SUBTITUTED ALKYLAMIDES | VERNALIS (OXFORD) LIMITED (GB) | 2004-04-06 | — | — | US | disclosed |