Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767454 | 0.92 | TACR1 (0.51) | TACR1MAPTBCHEACHEHPGD | |
| SCHEMBL6299831 | 0.90 | TACR1 (0.50) | TACR1 | |
| SCHEMBL6760489 | 0.90 | TACR1 (0.50) | TACR1 | |
| SCHEMBL6983476 | 0.84 | TACR1 (0.68) | TACR1 | |
| SCHEMBL6760502 | 0.82 | TACR1 (0.54) | TACR1 | |
| SCHEMBL6299711 | 0.81 | TACR1 (0.70) | TACR1MAPTBCHEACHE | |
| SCHEMBL6764654 | 0.79 | TACR1 (0.58) | TACR1BCHEACHE | |
| SCHEMBL6763276 | 0.77 | TACR1 (0.56) | TACR1MAPT | |
| SCHEMBL6767352 | 0.77 | TACR1 (0.68) | TACR1 | |
| SCHEMBL7778001 | 0.76 | TACR1 (0.71) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727255-B1 | BRAIN, NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY | 2004-04-27 | — | — | US | claimed |
| EP-0761219-A1 | 2-Acylaminopropanamines as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 1997-03-12 | — | — | EP | claimed |
| WO-1997007117-A1 | 2-ACYLAMINOPROPANAMINES AS GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 1997-02-27 | — | — | WO | claimed |
| EP-0729468-A1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-09-04 | — | — | EP | claimed |
| EP-0729468-A4 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1996-07-12 | — | — | EP | claimed |
| WO-1995014017-A1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1995-05-26 | — | — | WO | claimed |