Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | BRS3 | P32247 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764703 | 0.90 | TACR1 (0.64) | TACR1 | |
| SCHEMBL6767352 | 0.89 | TACR1 (0.68) | TACR1 | |
| SCHEMBL6764654 | 0.86 | TACR1 (0.58) | TACR1BRS3 | |
| SCHEMBL6299711 | 0.85 | TACR1 (0.70) | TACR1MAPTBRS3 | |
| SCHEMBL6763275 | 0.82 | TACR1 (0.82) | TACR1 | |
| SCHEMBL6767454 | 0.80 | TACR1 (0.51) | TACR1MAPTBRS3 | |
| SCHEMBL6762526 | 0.80 | TACR1 (0.79) | TACR1 | |
| SCHEMBL7035504 | 0.80 | TACR1 (0.63) | TACR1 | |
| SCHEMBL6762332 | 0.77 | TACR1 (0.47) | TACR1MAPT | |
| SCHEMBL6763282 | 0.77 | TACR1 (0.71) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727255-B1 | BRAIN, NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY | 2004-04-27 | — | — | US | claimed |
| EP-0729468-B1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2003-01-15 | — | — | EP | claimed |
| WO-1995014017-A1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1995-05-26 | — | — | WO | claimed |