Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.58 |
| ▸ | BRS3 | P32247 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763282 | 0.89 | TACR1 (0.71) | TACR1 | |
| SCHEMBL6299711 | 0.88 | TACR1 (0.70) | TACR1BRS3BCHEACHE | |
| SCHEMBL6767352 | 0.88 | TACR1 (0.68) | TACR1 | |
| SCHEMBL6763276 | 0.86 | TACR1 (0.56) | TACR1BRS3 | |
| SCHEMBL6764651 | 0.82 | TACR1 (0.82) | TACR1 | |
| SCHEMBL6767454 | 0.82 | TACR1 (0.51) | TACR1BRS3BCHEACHE | |
| SCHEMBL6762332 | 0.79 | TACR1 (0.47) | TACR1BCHEACHE | |
| SCHEMBL23629620 | 0.78 | TACR1 (0.72) | TACR1 | |
| SCHEMBL2997671 | 0.78 | TACR1 (0.72) | TACR1 | |
| SCHEMBL30307065 | 0.78 | TACR1 (0.72) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727255-B1 | BRAIN, NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY | 2004-04-27 | — | — | US | claimed |
| JP-2001509484-A | — | — | 2001-07-24 | — | — | JP | claimed |
| EP-0994712-A1 | INHIBITORS OF NEUTROPHIL MEDIATED OXIDANT PRODUCTION | ELI LILLY AND COMPANY (US) | 2000-04-26 | — | — | EP | claimed |
| WO-1999002163-A1 | INHIBITORS OF NEUTROPHIL MEDIATED OXIDANT PRODUCTION | ELI LILLY AND COMPANY (US) | 1999-01-21 | — | — | WO | claimed |
| EP-0761219-A1 | 2-Acylaminopropanamines as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 1997-03-12 | — | — | EP | claimed |
| EP-0729468-A1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-09-04 | — | — | EP | claimed |
| EP-0729468-A4 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1996-07-12 | — | — | EP | claimed |
| WO-1995014017-A1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1995-05-26 | — | — | WO | claimed |