Fluoride

Fluoride

SCHEMBL6762571

F.F.NCCC(N)CCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
THRB P10828 1/20 0.32
GABRR1 P24046 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL10427079 1.00 ALDH1A1 (0.41) ALDH1A1TSHRTHRBGABRR1
Fluoride SCHEMBL29045016 1.00
SCHEMBL120802 0.97
Bromide SCHEMBL29138753 0.94
Hydrochloric Acid SCHEMBL6387923 0.94 ALDH1A1 (0.41) ALDH1A1TSHRTHRBGABRR1
Alcohol SCHEMBL5181934 0.88 ALDH1A1 (0.37) ALDH1A1TSHRGABRR1
SCHEMBL364981 0.87
Fluoride SCHEMBL5041049 0.86 ALDH1A1 (0.35) ALDH1A1TSHR
Bromide SCHEMBL15392853 0.83
Hydrochloric Acid SCHEMBL447725 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4329715-A1 HAIR COMPOSITIONS COMPRISING AT LEAST 50% POLYOL L'OREAL (FR) 2024-03-06 EP disclosed
CN-111491696-B Dentifrice composition 加巴国际股份有限公司 2024-01-30 CN disclosed
CN-116568261-A Oral care compositions with amine fluoride 高露洁-棕榄公司 2023-08-08 CN disclosed
CN-111491696-A Dentifrice composition 加巴国际股份有限公司 2020-08-04 CN disclosed
CN-106913470-B Dentifrice composition 加巴国际控股有限公司 2020-06-16 CN disclosed
US-10328009-B1 Methods and compositions for improving the durability of color in artificially colored hair L'OREAL (FR) 2019-06-25 US disclosed
CN-102204872-B Oral care composition MCNEIL-PPC, INC. (US) 2015-08-12 CN disclosed
CN-102204877-A Oral care compositions MCNEIL PPC INC 2011-10-05 CN disclosed
CN-102204872-A Oral care compositions MCNEIL PPC INC 2011-10-05 CN disclosed
EP-1487419-A2 FAST DISSOLVING DOSAGE FORMS HAVING REDUCED FRIABILITY Elan Pharma International Limited (IE) 2004-12-22 EP disclosed
WO-2003080023-A2 FAST DISSOLVING DOSAGE FORMS HAVING REDUCED FRIABILITY ELAN PHARMA INTERNATIONAL LIMITED (IE) 2003-10-02 WO disclosed
EP-0944579-A1 AMINOHYDROFLUORIDES AND THEIR USE AS ORAL HYGIENE PREPARATIONS Gaba International (CH) 1999-09-29 EP disclosed
WO-1998022427-A1 AMINOHYDROFLUORIDES AND THEIR USE AS ORAL HYGIENE PREPARATIONS GABA INTERNATIONAL AG (CH) 1998-05-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10328009-B1 Methods and compositions for improving the durability of color in artificially colored hair TYR, COXFA4L2, OAT ALDH1A1 750/4885TSHR 4292/4885THRB 3906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.