SCHEMBL676270

SCHEMBL676270

N=C(N)NCCC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccc2ccccc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 5/20 0.51
HDAC4 P56524 4/20 0.48
HDAC3 O15379 3/20 0.48
HDAC7 Q8WUI4 3/20 0.48
HDAC2 Q92769 3/20 0.48
HDAC10 Q969S8 3/20 0.48
HDAC11 Q96DB2 3/20 0.48
HDAC8 Q9BY41 3/20 0.48
HDAC6 Q9UBN7 3/20 0.48
HDAC9 Q9UKV0 3/20 0.48
HDAC5 Q9UQL6 3/20 0.48
CCKBR P32239 1/20 0.44
EPHX1 P07099 2/20 0.43
MCHR1 Q99705 1/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
TPSAB1 Q15661 1/20 0.43
MEN1 O00255 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29458758 1.00 HDAC1 (0.51) HDAC1HDAC4HDAC3HDAC7HDAC2
SCHEMBL676271 1.00 HDAC1 (0.51) HDAC1HDAC4HDAC3HDAC7HDAC2
SCHEMBL10583019 1.00 HDAC1 (0.51) HDAC1HDAC4HDAC3HDAC7HDAC2
Hydrochloric Acid SCHEMBL10603655 0.99 HDAC1 (0.50) HDAC1HDAC4HDAC3HDAC7HDAC2
SCHEMBL8994359 0.92 HDAC1 (0.46) HDAC1HDAC4HDAC3HDAC7HDAC2
SCHEMBL8341786 0.88 HDAC1 (0.43) HDAC1HDAC4HDAC3HDAC7HDAC2
SCHEMBL8342382 0.88 MEN1 (0.43) HDAC1EPHX1CYP2C19MEN1KMT2A
Hydrochloric Acid SCHEMBL28274785 0.87 MEN1 (0.43) HDAC1EPHX1CYP2C19MEN1KMT2A
Hydrochloric Acid SCHEMBL28274778 0.87 MEN1 (0.43) HDAC1EPHX1CYP2C19MEN1KMT2A
SCHEMBL27352129 0.87 NPY4R (0.47) EPHX1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020218052-A1 PERIODONTOPATHIC BACTERIA DETECTION METHOD アドテック株式会社 2020-10-29 WO claimed
EP-3206723-A1 BIOLOGICAL INDICATOR American Sterilizer Company (US) 2017-08-23 EP claimed
US-9701968-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2017-07-11 US claimed
US-20160312263-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2016-10-27 US claimed
WO-2016060714-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2016-04-21 WO claimed
US-20160102335-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY 2016-04-14 US claimed
US-8507248-B2 Genetically engineered biological indicator AMERICAN STERILIZER COMPANY (US) 2013-08-13 US claimed
US-8173389-B2 Process for determining the effectiveness of a sterilization AMERICAN STERILIZER COMPANY (US) 2012-05-08 US claimed
US-20100267044-A1 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR FRANCISKOVICH PHILLIP P 2010-10-21 US claimed
EP-2084293-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
EP-0380932-B1 Solid phase test for the detection of periodontal disease in subgingival plaque LOESCHE WALTER J (US) 1996-08-21 EP claimed
US-5223403-A Device for diagnosing periodontal disease UNIVERSITY OF MICHIGAN (US) 1993-06-29 US claimed
EP-0523079-A1 SYSTEM FOR DIAGNOSING PERIODONTAL DISEASE THE UNIVERSITY OF MICHIGAN (US) 1993-01-20 EP claimed
US-5175089-A Quantitative analysis THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1992-12-29 US claimed
US-5116735-A Colorimetric assay, hydrolysis of chromogen THE UNIVERSITY OF MICHIGAN (US) 1992-05-26 US claimed
WO-1991014000-A1 SYSTEM FOR DIAGNOSING PERIODONTAL DISEASE THE UNIVERSITY OF MICHIGAN (US) 1991-09-19 WO claimed
EP-0380627-A4 METHOD FOR MONITORING PERIODONTAL DISEASE BY MONITORING ENDOTOXINS AND INFLAMMATORY AGENTS 1991-01-02 EP claimed
EP-0380932-A2 Solid phase test for the detection of periodontal disease in subgingival plaque Loesche, Walter J. (US) 1990-08-08 EP claimed
EP-0380627-A1 METHOD FOR MONITORING PERIODONTAL DISEASE BY MONITORING ENDOTOXINS AND INFLAMMATORY AGENTS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1990-08-08 EP claimed
WO-1990000620-A1 METHOD FOR MONITORING PERIODONTAL DISEASE BY MONITORING ENDOTOXINS AND INFLAMMATORY AGENTS THE TRUSTEES OF COLUMBIA UNIVERSITY (US) 1990-01-25 WO claimed