Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676270 | 1.00 | HDAC1 (0.51) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL29458758 | 1.00 | HDAC1 (0.51) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL10583019 | 1.00 | HDAC1 (0.51) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| Hydrochloric Acid SCHEMBL10603655 | 0.99 | HDAC1 (0.50) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL8994359 | 0.92 | HDAC1 (0.46) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL8341786 | 0.88 | HDAC1 (0.43) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL8342382 | 0.88 | MEN1 (0.43) | HDAC1EPHX1CYP2C19MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28274785 | 0.87 | MEN1 (0.43) | HDAC1EPHX1CYP2C19MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28274778 | 0.87 | MEN1 (0.43) | HDAC1EPHX1CYP2C19MEN1KMT2A | |
| SCHEMBL27352129 | 0.87 | NPY4R (0.47) | EPHX1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206723-A1 | BIOLOGICAL INDICATOR | American Sterilizer Company (US) | 2017-08-23 | — | — | EP | claimed |
| US-9701968-B2 | Biological indicator | AMERICAN STERILIZER COMPANY (US) | 2017-07-11 | — | — | US | claimed |
| US-20160312263-A1 | BIOLOGICAL INDICATOR | AMERICAN STERILIZER CO (US) | 2016-10-27 | — | — | US | claimed |
| WO-2016060714-A1 | BIOLOGICAL INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2016-04-21 | — | — | WO | claimed |
| US-20160102335-A1 | BIOLOGICAL INDICATOR | AMERICAN STERILIZER COMPANY | 2016-04-14 | — | — | US | claimed |
| US-20150011730-A1 | Cyclin Based Inhibitors of CDK2 and CDK4 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-01-08 | — | — | US | claimed |
| US-20140296484-A1 | Cyclin Based Inhibitors of CDK2 and CDK4 | UNIVERSITY OF SOUTH CAROLINA (US) | 2014-10-02 | — | — | US | claimed |
| US-8507248-B2 | Genetically engineered biological indicator | AMERICAN STERILIZER COMPANY (US) | 2013-08-13 | — | — | US | claimed |
| US-8173389-B2 | Process for determining the effectiveness of a sterilization | AMERICAN STERILIZER COMPANY (US) | 2012-05-08 | — | — | US | claimed |
| US-20100267044-A1 | GENETICALLY ENGINEERED BIOLOGICAL INDICATOR | FRANCISKOVICH PHILLIP P | 2010-10-21 | — | — | US | claimed |
| WO-2008082728-A2 | STERILIZATION INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2008-07-10 | — | — | WO | claimed |
| WO-2008079469-A2 | GENETICALLY ENGINEERED BIOLOGICAL INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2008-07-03 | — | — | WO | claimed |
| US-20080070231-A1 | Reporter genes taken up by microorganism, and repressor gene inhibits expression | AMERICAN STERILIZER COMPANY | 2008-03-20 | — | — | US | claimed |
| US-20080070272-A1 | STERILIZATION INDICATOR | AMERICAN STERILIZER COMPANY | 2008-03-20 | — | — | US | claimed |
| EP-0380932-B1 | Solid phase test for the detection of periodontal disease in subgingival plaque | LOESCHE WALTER J (US) | 1996-08-21 | — | — | EP | claimed |
| US-5223403-A | Device for diagnosing periodontal disease | UNIVERSITY OF MICHIGAN (US) | 1993-06-29 | — | — | US | claimed |
| EP-0523079-A1 | SYSTEM FOR DIAGNOSING PERIODONTAL DISEASE | THE UNIVERSITY OF MICHIGAN (US) | 1993-01-20 | — | — | EP | claimed |
| US-5116735-A | Colorimetric assay, hydrolysis of chromogen | THE UNIVERSITY OF MICHIGAN (US) | 1992-05-26 | — | — | US | claimed |
| WO-1991014000-A1 | SYSTEM FOR DIAGNOSING PERIODONTAL DISEASE | THE UNIVERSITY OF MICHIGAN (US) | 1991-09-19 | — | — | WO | claimed |
| EP-0380932-A2 | Solid phase test for the detection of periodontal disease in subgingival plaque | Loesche, Walter J. (US) | 1990-08-08 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011730-A1 | Cyclin Based Inhibitors of CDK2 and CDK4 | CDK4, CDK2, CDK8 | HDAC1 389/4885HDAC4 527/4885HDAC3 1175/4885 |
| US-20140296484-A1 | Cyclin Based Inhibitors of CDK2 and CDK4 | CDK4, CDK2, CDK8 | HDAC1 389/4885HDAC4 527/4885HDAC3 1175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.