Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676270 | 1.00 | HDAC1 (0.51) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL676271 | 1.00 | HDAC1 (0.51) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL10583019 | 1.00 | HDAC1 (0.51) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| Hydrochloric Acid SCHEMBL10603655 | 0.99 | HDAC1 (0.50) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL8994359 | 0.92 | HDAC1 (0.46) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL8341786 | 0.88 | HDAC1 (0.43) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL8342382 | 0.88 | MEN1 (0.43) | HDAC1EPHX1CYP2C19MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28274785 | 0.87 | MEN1 (0.43) | HDAC1EPHX1CYP2C19MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28274778 | 0.87 | MEN1 (0.43) | HDAC1EPHX1CYP2C19MEN1KMT2A | |
| SCHEMBL27352129 | 0.87 | NPY4R (0.47) | EPHX1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250161468-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
| US-20240390507-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2024-11-28 | — | — | US | disclosed |
| CN-113924492-B | Detection of microbial endotoxin in oral samples using an aptamer | 宝洁公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-219951029-U | Enzyme reaction detection device | 武汉简为医疗科技有限公司 | 2023-11-03 | — | — | CN | disclosed |
| US-11643661-B2 | Detection of microbial endotoxins in oral samples using aptamers | THE PROCTER & GAMBLE COMPANY (US) | 2023-05-09 | — | — | US | disclosed |
| CN-109988228-B | Mongolian astragalus disease course related protein and crystal, growth method and application thereof | 山西中医药大学 | 2022-11-25 | — | — | CN | disclosed |
| US-20220119496-A1 | INHIBITORS OF CYSTEINE PEPTIDASES ISOLATED FROM NATURAL RAW MATERIALS AND USE OF THE INHIBITORS IN MEDICINE AND VETERINARY MEDICINE | RAPAK, Andrzej Marek (PL) | 2022-04-21 | — | — | US | disclosed |
| EP-3966330-A2 | DETECTION OF MICROBIAL ENDOTOXINS IN ORAL SAMPLES USING APTAMERS | The Procter & Gamble Company (US) | 2022-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250161468-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRL1 | HDAC1 106/4885HDAC4 794/4885HDAC3 179/4885 |
| US-20240390507-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRL1 | HDAC1 106/4885HDAC4 794/4885HDAC3 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.