Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.43 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.43 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.43 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16389120 | 0.98 | KDM4E (0.49) | KDM4EMEN1RECQLKMT2AALOX15 | |
| SCHEMBL1108082 | 0.98 | KDM4E (0.49) | KDM4EMEN1RECQLKMT2AALOX15 | |
| SCHEMBL6759814 | 0.98 | KDM4E (0.49) | KDM4EMEN1RECQLKMT2AALOX15 | |
| SCHEMBL6763903 | 0.95 | KMT2A (0.55) | KDM4EMEN1RECQLKMT2AALOX15 | |
| SCHEMBL3607900 | 0.89 | ALOX15 (0.45) | KDM4EMEN1RECQLKMT2AALOX15 | |
| SCHEMBL31454171 | 0.88 | ALDH1A1 (0.52) | KDM4EMEN1RECQLKMT2AALOX15 | |
| SCHEMBL18078285 | 0.86 | ALOX15 (0.48) | KDM4EMEN1RECQLKMT2AALOX15 | |
| SCHEMBL6766240 | 0.85 | ALOX15 (0.47) | KDM4EMEN1RECQLKMT2AALOX15 | |
| SCHEMBL16671445 | 0.85 | POLB (0.54) | KDM4EMEN1RECQLKMT2AALOX15 | |
| SCHEMBL6761527 | 0.84 | ALOX15 (0.46) | KDM4EMEN1RECQLKMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | VALENZUELA CORTES CARMEN MARIA (CL) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | PDE3A, PDE3B, PDE12 | KDM4E 697/4885MEN1 3117/4885RECQL 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.