Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 12/20 | 0.48 |
| ▸ | CA4 | P22748 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | HRAS | P01112 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759349 | 0.91 | GRIA4 (0.49) | GRIA4CA4CA12CA1CA2 | |
| SCHEMBL6763801 | 0.88 | GRIA4 (0.54) | GRIA4GRIA2GRIA1GRIA3HRAS | |
| SCHEMBL6573578 | 0.88 | GRIA4 (0.50) | GRIA4CA4CA12CA1CA2 | |
| SCHEMBL6763714 | 0.85 | MTNR1A (0.49) | GRIA4CA4CA12CA1CA2 | |
| SCHEMBL6765777 | 0.84 | ALDH1A1 (0.55) | GRIA4CA12CA1CA2CA9 | |
| SCHEMBL6766144 | 0.84 | GRIA4 (0.45) | GRIA4CA4CA12CA1CA2 | |
| SCHEMBL6762959 | 0.83 | KDM4E (0.47) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL6761041 | 0.82 | PPARG (0.58) | GRIA4GRIA2 | |
| SCHEMBL13256275 | 0.82 | GRIA4 (0.64) | GRIA4GRIA2GRIA1GRIA3ABCB11 | |
| SCHEMBL13255828 | 0.82 | GRIA4 (0.64) | GRIA4GRIA2GRIA1GRIA3ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | DAVISON JOSHUA ZWICK (US) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | GRIN1, GRIN2A, GRIA1 | GRIA4 9/4885CA4 2818/4885CA12 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.