Artocarpetin

Artocarpetin

SCHEMBL676337

COc1cc(O)c2c(=O)cc(-c3ccc(O)cc3O)oc2c1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IP6K2 Q9UHH9 4/20 0.76
FLT3 P36888 3/20 0.76
MKNK2 Q9HBH9 2/20 0.76
PTGS1 P23219 2/20 0.74
BACE1 P56817 2/20 0.74
TYR P14679 1/20 0.74
PTPN1 P18031 1/20 0.74
PTPN12 Q05209 1/20 0.74
PTPN22 Q9Y2R2 1/20 0.74
MAOB P27338 3/20 0.71
CYP19A1 P11511 2/20 0.71
MAPT P10636 5/20 0.70
CYP3A4 P08684 4/20 0.70
CYP2C9 P11712 4/20 0.70
CYP2C19 P33261 4/20 0.70
NPC1 O15118 3/20 0.70
ABCB1 P08183 2/20 0.70
TSHR P16473 2/20 0.70
ABCG2 Q9UNQ0 2/20 0.70
CYP1B1 Q16678 5/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Artocarpetin SCHEMBL29435858 1.00 IP6K2 (0.76) IP6K2FLT3MKNK2PTGS1BACE1
SCHEMBL29435855 0.88 CYP3A4 (0.76) IP6K2FLT3MKNK2PTGS1BACE1
SCHEMBL26117399 0.88 CYP3A4 (0.76) IP6K2FLT3MKNK2PTGS1BACE1
Genkwanin SCHEMBL866123 0.86 FLT3 (1.00) IP6K2FLT3MKNK2PTGS1BACE1
Genkwanin SCHEMBL29445006 0.86 FLT3 (1.00) IP6K2FLT3MKNK2PTGS1BACE1
Norartocarpetin SCHEMBL1546435 0.86 BACE1 (1.00) IP6K2FLT3MKNK2PTGS1BACE1
Norartocarpetin SCHEMBL29435851 0.86 BACE1 (1.00) IP6K2FLT3MKNK2PTGS1BACE1
Apigenin Dimethylether SCHEMBL29392759 0.83 MAOB (1.00) IP6K2FLT3MKNK2PTGS1BACE1
Apigenin Dimethylether SCHEMBL1176691 0.83 MAOB (1.00) IP6K2FLT3MKNK2PTGS1BACE1
SCHEMBL30721041 0.83 CYP3A4 (0.69) IP6K2FLT3MKNK2PTGS1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
US-20230321197-A1 Polyphenolic Insulin KIMBALL WESTWARD LLC (US) 2023-10-12 US disclosed
US-20190142940-A1 Method and system for effecting changes in pigmented tissue MOAZED KAMBIZ THOMAS (US) 2019-05-16 US disclosed
US-9744237-B2 Method and system for effecting changes in pigmented tissue MOAZED KAMBIZ THOMAS (US) 2017-08-29 US disclosed
US-20120207809-A1 Method and system for effecting changes in pigmented tissue MOAZED KAMBIZ THOMAS (US) 2012-08-16 US disclosed
US-20120076848-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2012-03-29 US disclosed
US-20110280909-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2011-11-17 US disclosed
WO-2011011065-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2011-01-27 WO disclosed
WO-2010087983-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2010-08-05 WO disclosed