Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Methylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL7629256 | 0.96 | — | — | |
| Hydroxyamine SCHEMBL6141650 | 0.92 | — | — | |
| Hydroxyamine SCHEMBL7541307 | 0.92 | BLM (0.44) | — | |
| SCHEMBL2058760 | 0.91 | CA5A (0.46) | — | |
| SCHEMBL1904 | 0.91 | — | — | |
| SCHEMBL126970 | 0.91 | — | — | |
| Ethylamine SCHEMBL9647576 | 0.88 | — | — | |
| Methyl Alcohol SCHEMBL23421569 | 0.87 | — | — | |
| SCHEMBL20533683 | 0.87 | — | — | |
| SCHEMBL6917272 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2633872-B1 | CARRIER FOR BLOOD COMPONENT ADSORPTION AND BLOOD COMPONENT ADSORPTION COLUMN | TORAY INDUSTRIES (JP) | 2019-04-24 | — | — | EP | disclosed |
| US-9802178-B2 | Carrier for blood component adsorption and blood component adsorption column | TORAY INDUSTRIES, INC. (JP) | 2017-10-31 | — | — | US | disclosed |
| EP-2633872-A1 | CARRIER FOR BLOOD COMPONENT ADSORPTION AND BLOOD COMPONENT ADSORPTION COLUMN | Toray Industries, Inc. (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-20130220912-A1 | CARRIER FOR BLOOD COMPONENT ADSORPTION AND BLOOD COMPONENT ADSORPTION COLUMN | TORAY INDUSTRIES, INC. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-6727341-B2 | Stable and high solids aqueous dispersions of blocked polyisocyanates | DEGUSSA AG (DE) | 2004-04-27 | — | — | US | disclosed |
| US-20020025996-A1 | Stable and high solids aqueous dispersions of blocked polyisocyanates | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2002-02-28 | — | — | US | disclosed |
| US-6348521-B1 | Stable and high solids aqueous dispersions of blocked polyisocyanates | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2002-02-19 | — | — | US | disclosed |
| EP-1068390-A1 | METHOD FOR IMPROVED WET STRENGTH PAPER | Kimberly-Clark Worldwide, Inc. (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6096805-A | Stable and high solids aqueous dispersions of blocked polyisocyanates | HUELS AKTIENGESELLSCHAFT (DE) | 2000-08-01 | — | — | US | disclosed |
| WO-1999045201-A1 | METHOD FOR IMPROVED WET STRENGTH PAPER | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1999-09-10 | — | — | WO | disclosed |
| US-RE29585-E | DYEING WOOL | CIBA-GEIGY CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4067864-A | FOR CELLULOSE OR POLYAMIDES | CIBA-GEIGY AG (CH) | 1978-01-10 | — | — | US | disclosed |
| US-4039523-A | YELLOW | CIBA-GEIGY AG (CH) | 1977-08-02 | — | — | US | disclosed |
| US-4036825-A | DYES FOR CELLULOSE OR NITROGEN-CONTAINING FIBERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
| US-4017477-A | 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs | CIBA-GEIGY AG (CH) | 1977-04-12 | — | — | US | disclosed |
| US-4001203-A | Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |
| US-4001205-A | WATER-SOLUBLE, FIBER-REACTIVE PHENYLAZODIHYDROXY, METHYL, CYANOPYRIDINE DYESTUFFS | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |
| US-3971738-A | Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3957728-A | MODIFIED WITH S-TRIAZINES; ABSORBENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
| US-3956263-A | 4-Methyl-2,6-dihydroxy-3-cyanopyridine containing dyestuffs | CIBA-GEIGY AG (CH) | 1976-05-11 | — | — | US | disclosed |