Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Hydroxyamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL6141650 | 1.00 | — | — | |
| Methylamine SCHEMBL6763378 | 0.92 | — | — | |
| SCHEMBL2058760 | 0.91 | CA5A (0.46) | BLMCYP2C19LMNASLC6A6CA1 | |
| SCHEMBL1904 | 0.91 | — | — | |
| SCHEMBL126970 | 0.91 | — | — | |
| Methylamine SCHEMBL7629256 | 0.88 | — | — | |
| Ethylamine SCHEMBL9647576 | 0.88 | — | — | |
| Methyl Alcohol SCHEMBL23421569 | 0.87 | — | — | |
| SCHEMBL20533683 | 0.87 | — | — | |
| SCHEMBL7587151 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646327-A | Method for preparing hydroxylamines using vinylic compounds without base neutralization and reaction mixture produced thereby | EASTMAN KODAK COMPANY (US) | 1997-07-08 | — | — | US | claimed |
| EP-0761647-A2 | Improved method for preparing hydroxylamines using vinylic compounds without base neutralization and reaction mixture produced thereby | EASTMAN KODAK COMPANY (US) | 1997-03-12 | — | — | EP | claimed |
| US-6444414-B1 | A BLACK-AND-WHITE PHOTOGRAPHIC DEVELOPING COMPOSITION HAS IMPROVED STABILITY AND IS MORE COMPATIBLE WITH THE ENVIRONMENT WHEN DISCARDED. | EASTMAN KODAK COMPANY | 2002-09-03 | — | — | US | disclosed |
| EP-1199597-A1 | Ascorbic acid developing compositions stabilized with sulfo compound and methods of use | EASTMAN KODAK COMPANY (US) | 2002-04-24 | — | — | EP | disclosed |
| US-5827635-A | DEVELOPING, BLEACHING, FIXING, WASHING AND RINSING; USING SPECIFIC HYDROXYAMINE DERIVATIVE AS AN ANTIOXIDANT | EASTMAN KODAK COMPANY (US) | 1998-10-27 | — | — | US | disclosed |
| US-5646327-A | Method for preparing hydroxylamines using vinylic compounds without base neutralization and reaction mixture produced thereby | EASTMAN KODAK COMPANY (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0761647-A2 | Improved method for preparing hydroxylamines using vinylic compounds without base neutralization and reaction mixture produced thereby | EASTMAN KODAK COMPANY (US) | 1997-03-12 | — | — | EP | disclosed |