SCHEMBL676346

SCHEMBL676346

NNC(=O)C1=CC(=O)C=CC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.35
ALDH1A1 P00352 5/20 0.34
MAPT P10636 4/20 0.34
RECQL P46063 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
MEN1 O00255 1/20 0.34
HPGD P15428 1/20 0.34
ALOX12 P18054 1/20 0.34
KMT2A Q03164 1/20 0.34
MPO P05164 2/20 0.34
CYP3A4 P08684 2/20 0.34
BLM P54132 2/20 0.34
P2RX7 Q99572 1/20 0.34
KDM5A P29375 1/20 0.34
GFER P55789 1/20 0.34
PMP22 Q01453 1/20 0.34
HIF1A Q16665 1/20 0.34
KDM4E B2RXH2 4/20 0.33
LMNA P02545 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8049734 0.80 ALDH1A1 (0.36) NR4A1ALDH1A1MAPTRECQLTDP1
SCHEMBL28327160 0.74 TDP1 (0.42) NR4A1ALDH1A1MAPTRECQLTDP1
SCHEMBL7888132 0.74 POLB (0.35) ALDH1A1MAPTMEN1HPGDKMT2A
SCHEMBL2257187 0.70 ALDH1A1 (0.44) NR4A1ALDH1A1MAPTRECQLTDP1
SCHEMBL28198484 0.70 ALDH1A1 (0.41) NR4A1ALDH1A1MAPTRECQLTDP1
SCHEMBL1287162 0.70 ERBB2 (0.39) NR4A1ALDH1A1MAPTRECQLTDP1
SCHEMBL6850637 0.70 SETD7 (0.51) ALDH1A1MAPTRECQLTDP1MEN1
SCHEMBL27913580 0.70 ACHE (0.37) NR4A1ALDH1A1MAPTRECQLTDP1
Water SCHEMBL28540739 0.68 ERBB2 (0.38) NR4A1ALDH1A1MAPTRECQLTDP1
SCHEMBL26444866 0.68 ALDH1A1 (0.37) NR4A1ALDH1A1MAPTRECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3302569-A1 CROSS-LINKED HYALURONIC ACID FOR DRUG DELIVERY AND PHARMACEUTICAL PREPARATION USING SAME Albatross Technologies Limited (MT) 2018-04-11 EP claimed
WO-2016191850-A1 CROSS-LINKED HYALURONIC ACID FOR DRUG DELIVERY AND PHARMACEUTICAL PREPARATION USING SAME ALURON BIOPHARMA INC. (CA) 2016-12-08 WO claimed
US-20160346398-A1 CROSS-LINKED HYALURONIC ACID FOR DRUG DELIVERY AND PHARMACEUTICAL PREPARATION USING SAME ALBATROSS TECHNOLOGIES LIMITED (MT) 2016-12-01 US claimed
CN-104127469-A New application of olive leaf crude extract and tumor therapeutic drug combined kit thereof SHANGHAI YUXIAN MEDICAL TECHNOLOGY CO LTD 2014-11-05 CN claimed
US-20080312130-A1 DRUG DELIVERY VEHICLE FOR CANCER THERAPY, PROCESS FOR PRODUCING THE SAME, AND PHARMACEUTICAL PREPARATION USING THE SAME GENOMLDEA INC. (JP) 2008-12-18 US claimed
CN-1923173-A Anti-cancer drugs slow release agent comprising anticancer antibiotics and booster thereof JINAN KANGQUAN PHARMACEUTICAL (CN) 2007-03-07 CN claimed
CN-1857723-A Slow released anticancer medicine preparation with both amrubicin and its synergist KANGQUAN MEDICINE SCI TECH CO (CN) 2006-11-08 CN claimed
CN-1634584-A Anti-cancer medicine composition containing antimetabolite SHANDONG LANJIN BIOENGINEERING (CN) 2005-07-06 CN claimed
US-20230010871-A1 COMPLEXES COMPRISING A CARBOHYDRATE POLYMER AND AN ACTIVE INGREDIENT AND PROCESSES FOR THEIR PREPARATION FOLIUM LABS INC. (CA) 2023-01-12 US disclosed
WO-2021113986-A1 COMPLEXES COMPRISING A CARBOHYDRATE POLYMER AND AN ACTIVE INGREDIENT AND PROCESSES FOR THEIR PREPARATION FOLIUM LABS INC. (CA) 2021-06-17 WO disclosed
CN-104127469-B The new application of Chinese olive tree Leave extract 上海御先医药科技有限公司 2018-08-28 CN disclosed
EP-3302569-A1 CROSS-LINKED HYALURONIC ACID FOR DRUG DELIVERY AND PHARMACEUTICAL PREPARATION USING SAME Albatross Technologies Limited (MT) 2018-04-11 EP disclosed
WO-2016191850-A1 CROSS-LINKED HYALURONIC ACID FOR DRUG DELIVERY AND PHARMACEUTICAL PREPARATION USING SAME ALURON BIOPHARMA INC. (CA) 2016-12-08 WO disclosed
US-20160346398-A1 CROSS-LINKED HYALURONIC ACID FOR DRUG DELIVERY AND PHARMACEUTICAL PREPARATION USING SAME ALBATROSS TECHNOLOGIES LIMITED (MT) 2016-12-01 US disclosed
CN-1679944-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN disclosed
CN-1679950-A Anticarcinogenic internal implant agent LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN disclosed
CN-1634584-A Anti-cancer medicine composition containing antimetabolite SHANDONG LANJIN BIOENGINEERING (CN) 2005-07-06 CN disclosed
CN-1634586-A Anti-cancer medicine composition SHANDONG LANJIN BIOENGINEERING (CN) 2005-07-06 CN disclosed
US-5616609-A ALCOHOL EXTRACTION OF STELLERAMACRIN A AND B FROM RUI-XIANG-LANG-DU, A CHINESE PLANT IKEKAWA, TETSURO (JP) 1997-04-01 US disclosed
EP-0627436-A1 CARCINOSTATIC COMPOUND AND PRODUCTION THEREOF TSUMURA & CO. (JP) 1994-12-07 EP disclosed