Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | B3GNT2 | Q9NY97 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16548565 | 0.88 | POLB (0.48) | AURKALMNAHTR3A | |
| SCHEMBL6766028 | 0.85 | HTR3A (0.47) | AURKAB3GNT2LMNAPGRHTR3A | |
| SCHEMBL21156818 | 0.83 | LMNA (0.51) | B3GNT2LMNAPGRPSMB8LRRK2 | |
| SCHEMBL1759132 | 0.83 | B3GNT2 (0.61) | AURKAB3GNT2LMNAPGRMAOB | |
| SCHEMBL1759187 | 0.82 | CREBBP (0.51) | B3GNT2LMNAPGRPSMB8MAOB | |
| SCHEMBL25195141 | 0.81 | LMNA (0.50) | AURKAB3GNT2LMNAPGRPSMB8 | |
| SCHEMBL6763764 | 0.81 | BRD4 (0.57) | B3GNT2LMNAPGRMAPKAPK2MAOB | |
| SCHEMBL12673423 | 0.79 | B3GNT2 (0.49) | B3GNT2LMNAPGRMAOB | |
| SCHEMBL20660794 | 0.78 | LMNA (0.46) | AURKAB3GNT2LMNAPGRHTR3A | |
| SCHEMBL21156822 | 0.78 | LMNA (0.46) | B3GNT2LMNAPGRHTR3AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |