SCHEMBL676352

SCHEMBL676352

C=C(CC(O)(O)O)C(=O)OCCC(CO)(CO)CO

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3862116 0.81 ALDH1A1 (0.33) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL27845822 0.81 TSHR (0.39)
SCHEMBL4583435 0.80 THRB (0.35) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL28437629 0.78 ALDH1A1 (0.37) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL213774 0.76 THRB (0.50) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL11805529 0.76 ALDH1A1 (0.34) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL4961106 0.75 THRB (0.42) ALDH1A1
SCHEMBL9722097 0.73 TSHR (0.35) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL248339 0.71 ALDH1A1 (0.35) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Methacrylic Acid SCHEMBL2711894 0.71 THRB (0.46) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240085790-A1 METHOD OF PREPARING FILM AND COMPOSITION THEREFOR DOW SILICONES CORPORATION 2024-03-14 US disclosed
EP-4263712-A1 METHOD OF PREPARING FILM AND COMPOSITION THEREFOR Dow Silicones Corporation (US) 2023-10-25 EP disclosed
WO-2022132906-A1 METHOD OF PREPARING FILM AND COMPOSITION THEREFOR DOW SILICONES CORPORATION (US) 2022-06-23 WO disclosed
US-10676594-B2 Reactive compositions containing mercapto-functional silicon compound MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-06-09 US disclosed
EP-3283577-B1 REACTIVE COMPOSITIONS CONTAINING MERCAPTO-FUNCTIONAL SILICON COMPOUND MOMENTIVE PERFORMANCE MAT INC (US) 2019-07-17 EP disclosed
WO-2019060614-A1 AQUEOUS COATING COMPOSITION DOW SILICONES CORPORATION (US) 2019-03-28 WO disclosed
US-20190010309-A1 REACTIVE COMPOSITIONS CONTAINING MERCAPTO-FUNCTIONAL SILICON COMPOUND MOMENTIVE PERFORMANCE MATERIALS INC. 2019-01-10 US disclosed
US-10172779-B2 Copolymer having carbosiloxane dendrimer structure and composition and cosmetic containing the same DOW CORNING TORAY CO., LTD. (JP) 2019-01-08 US disclosed
US-10106671-B2 Reactive compositions containing mercapto-functional silicon compound MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-10-23 US disclosed
EP-3283577-A1 REACTIVE COMPOSITIONS CONTAINING MERCAPTO-FUNCTIONAL SILICON COMPOUND Momentive Performance Materials Inc. (US) 2018-02-21 EP disclosed
US-7842755-B2 Dimethylvinylsilanol-endcapped polymethylphenylsiloxane, an organohydrogenpolysiloxane, a copolymer of a vinyl monomer and a vinyl monomer with hydrosilyl groups, platinum catalyst; two-stage thermal curing; high refractive index, light transmittance, adhesion, especially to thermoplastic resins DOW CORNING TORAY COMPANY, LTD. (JP) 2010-11-30 US disclosed
EP-1095953-B1 Silicone-grafted vinyl copolymer emulsion composition DOW CORNING TORAY CO LTD (JP) 2009-03-04 EP disclosed
US-20080262158-A1 Dimethylvinylsilanol-endcapped polymethylphenylsiloxane, an organohydrogenpolysiloxane, a copolymer of a vinyl monomer and a vinyl monomer with hydrosilyl groups, platinum catalyst; two-stage thermal curing; high refractive index, light transmittance, adhesion, especially to thermoplastic resins DOW CORNING TORAY CO., LTD. (JP) 2008-10-23 US disclosed
EP-1781741-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER DOW CORNING TORAY CO LTD (JP) 2008-08-27 EP disclosed
EP-1781741-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER Dow Corning Toray Co., Ltd. (JP) 2007-05-09 EP disclosed
WO-2006011676-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER DOW CORNING TORAY CO., LTD. (JP) 2006-02-02 WO disclosed
US-6602949-B2 Copolymer of a vinyl monomer, a branched organosilicon compound having an ethenically unsaturated group, and a radically polymerizable surfactant; water repellent coatings with printability, storage stability DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-08-05 US disclosed
US-6534590-B1 Vinyl monomer, carbosiloxane dendrimer, surfactant, and free radical initiator; waterproof coatings; storage stability DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-03-18 US disclosed
US-20020120039-A1 Vinyl copolymer emulsion DOW TORAY CO., LTD. (JP) 2002-08-29 US disclosed
EP-1095953-A2 Silicone-grafted vinyl copolymer emulsion composition Dow Corning Toray Silicone Company, Ltd. (JP) 2001-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10172779-B2 Copolymer having carbosiloxane dendrimer structure and composition and cosmetic containing the same DCLRE1A, MC1R, ADGRE5 ALDH1A1 1363/4885TP53 446/4885CYP3A4 2859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.