Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | SETD1B | Q9UPS6 | 1/20 | 0.52 |
| ▸ | OGG1 | O15527 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761210 | 0.83 | MCL1 (0.54) | MCL1ALDH1A1GAALMNAHDAC8 | |
| SCHEMBL11586955 | 0.82 | MCL1 (0.71) | MCL1ALDH1A1GAATP53KDM4E | |
| SCHEMBL4411547 | 0.79 | MMP3 (0.54) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL6761507 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL11531093 | 0.78 | MCL1 (0.60) | MCL1ALDH1A1GAALMNASETD1B | |
| SCHEMBL7827991 | 0.78 | MCL1 (0.69) | MCL1ALDH1A1GAALMNASETD1B | |
| SCHEMBL4411183 | 0.77 | KDM4E (0.58) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL21533505 | 0.76 | SETD1B (0.72) | SETD1B | |
| SCHEMBL6764958 | 0.76 | KAT6A (0.52) | MCL1GAALMNAKMT2A | |
| SCHEMBL6769558 | 0.76 | KMT2A (0.50) | MCL1ALDH1A1GAALMNASETD1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730704-B2 | REACTING AN ARYLOXYPROPIONIC ACID HYDRAZIDE WITH AN ARYLSULFONYL CHLORIDE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2004-05-04 | — | — | US | disclosed |
| US-20030187065-A1 | 1-(ARYLOXY)PROPIONOYL-2-ARYLSULFONYL HYDRAZINES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS HYPOGLYCEMIC AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187065-A1 | 1-(ARYLOXY)PROPIONOYL-2-ARYLSULFONYL HYDRAZINES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS HYPOGLYCEMIC AGENTS | IAPP, DPP4, GLP1R | MCL1 2881/4885ALDH1A1 292/4885GAA 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.