Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL8552009 | 0.80 | TSHR (0.46) | MAPK1ALDH1A1CYP3A4LMNACYP1A2 | |
| Phenol SCHEMBL9645845 | 0.80 | TDP1 (0.46) | GAAESR1ESR2POLBNPC1 | |
| Parachlorophenol SCHEMBL1045637 | 0.74 | MAPK1 (0.58) | MAPK1ALDH1A1MAPTGAAKDM4E | |
| Parachlorophenol SCHEMBL29039840 | 0.74 | MAPK1 (0.58) | MAPK1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL4126964 | 0.72 | F2 (0.50) | MAPK1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL9645847 | 0.72 | LMNA (0.46) | GAAESR1F2PRSS1PRSS2 | |
| Parachlorophenol SCHEMBL28880338 | 0.72 | MAPK1 (0.56) | MAPK1ALDH1A1MAPTGAAKDM4E | |
| Parachlorophenol SCHEMBL28864 | 0.71 | — | — | |
| Parachlorophenol SCHEMBL7730292 | 0.71 | MAPK1 (0.65) | MAPK1ALDH1A1MAPTKDM4EESR1 | |
| Parachlorophenol SCHEMBL6119005 | 0.71 | MAPK1 (0.65) | MAPK1ALDH1A1MAPTKDM4EESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727359-B2 | REACTING PHENOXIDE SULFONYLCHLORIDE AND ACETOACETAMIDE-N-SULFONYL PHENOXIDE AND AMMONIA USING CATALYST | BDL CORPORATION | 2004-04-27 | — | — | US | disclosed |
| US-20030065172-A1 | Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor | BDL CORPORATION | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065172-A1 | Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor | PDXK, ITK, KHK | MAPK1 1352/4885ALDH1A1 636/4885MAPT 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.