Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652874 | 0.83 | CYP2D6 (0.48) | SMN1; SMN2GAACYP2D6CYP1A2GRIN2D | |
| SCHEMBL4953088 | 0.80 | SMN1; SMN2 (0.45) | CES1SMN1; SMN2GAASRCCYP2D6 | |
| SCHEMBL390943 | 0.79 | CES1 (0.52) | CES1SMN1; SMN2SRCCYP2C19HIF1A | |
| SCHEMBL11789186 | 0.79 | CES1 (0.50) | CES1SMN1; SMN2SRCCYP1A2CYP2C19 | |
| SCHEMBL476563 | 0.78 | CES1 (0.47) | CES1SMN1; SMN2GAASRCCYP2D6 | |
| SCHEMBL6321356 | 0.78 | CHRM2 (0.48) | CES1SMN1; SMN2SRCCYP2D6CYP1A2 | |
| SCHEMBL6200772 | 0.78 | CES1 (0.44) | CES1SMN1; SMN2GAASRCCYP2D6 | |
| SCHEMBL8462452 | 0.78 | CES1 (0.45) | CES1SMN1; SMN2GAASRCCYP2D6 | |
| SCHEMBL4810206 | 0.78 | CES1 (0.44) | CES1SMN1; SMN2GAASRCCYP2D6 | |
| SCHEMBL4009225 | 0.77 | KCNN4 (0.55) | CES1SMN1; SMN2GAASRCCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110073470-A | Semiconductor machining adhesive tape | 古河电气工业株式会社 | 2019-07-30 | — | — | CN | disclosed |
| US-9926276-B2 | Substituted benzamides with activity towards EP4 receptors | DRACONIS PHARMA, S.L. (ES) | 2018-03-27 | — | — | US | disclosed |
| CN-107431007-A | The back side grinding surface protection tape of semiconductor wafer and the grinding processing method of semiconductor wafer | 古河电气工业株式会社 | 2017-12-01 | — | — | CN | disclosed |
| US-20150376129-A1 | SUBSTITUTED BENZAMIDES WITH ACTIVITY TOWARDS EP4 RECEPTORS | DRACONIS PHARMA, S.L. (ES) | 2015-12-31 | — | — | US | disclosed |
| US-6730765-B1 | CURABLE ORGANOSILOXANE OLIGOMERS CONTAIN MALEAMIC ACID FUNCTIONALITY | NCR CORPORATION | 2004-05-04 | — | — | US | disclosed |
| US-5565246-A | THERMOGRAPHY | BIOMETRIC IMAGING INC. | 1996-10-15 | — | — | US | disclosed |
| US-4112182-A | CELLULOSE ESTER ARTICLE COATED WITH RADIATION CURABLE UNSATURATED CELLULOSE ESTER- ACRYLATE | EASTMAN KODAK COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376129-A1 | SUBSTITUTED BENZAMIDES WITH ACTIVITY TOWARDS EP4 RECEPTORS | PTGER4, PTGER1, PTGER2 | CES1 544/4885SMN1; SMN2 4035/4885GAA 2950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.