Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953088 | 0.83 | SMN1; SMN2 (0.45) | CES1SMN1; SMN2GAASRCCYP1A2 | |
| SCHEMBL1264958 | 0.79 | CES1 (0.44) | CES1SMN1; SMN2GAASRCPGR | |
| SCHEMBL10531130 | 0.79 | SRC (0.41) | CES1SMN1; SMN2GAASRCPGR | |
| SCHEMBL6763904 | 0.78 | CES1 (0.47) | CES1SMN1; SMN2GAASRCCYP1A2 | |
| SCHEMBL8462267 | 0.78 | CES1 (0.50) | CES1SMN1; SMN2SRCCYP1A2CYP2D6 | |
| SCHEMBL11424538 | 0.77 | CES1 (0.45) | CES1SMN1; SMN2SRCCYP2C19MAPT | |
| SCHEMBL4920913 | 0.77 | CES1 (0.45) | CES1SMN1; SMN2SRCCYP2C19MAPT | |
| SCHEMBL3003131 | 0.77 | CES1 (0.50) | CES1SMN1; SMN2GAASRCPGR | |
| SCHEMBL11744711 | 0.76 | CES1 (0.44) | CES1SMN1; SMN2SRCCYP1A2CYP2D6 | |
| SCHEMBL8459206 | 0.74 | MMP8 (0.50) | CES1SMN1; SMN2SRCCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138743-C | 1, 3-diketone compound | ض� | 2004-02-18 | — | — | CN | disclosed |
| CN-1054139-C | Catalyst component for the polymerization of olefins and catalyst obtained | MONTELL NORTH AMERICAN INC (US) | 2000-07-05 | — | — | CN | disclosed |
| CN-1257061-A | 1, 3-diketone compound | MONTELL NORTH AMERICAN INC (US) | 2000-06-21 | — | — | CN | disclosed |
| EP-0646605-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-06-02 | — | — | EP | disclosed |
| US-5468704-A | Comprising titanium halide or halogen alcoholate supported on magnesium halide and a diketone electron donor; preparing polypropylene of high isotacticity | MONTELL NORTH AMERICA INC. (US) | 1995-11-21 | — | — | US | disclosed |
| CN-1105671-A | Components and catalysts for olefin polymerization | HIMONT INC (US) | 1995-07-26 | — | — | CN | disclosed |
| EP-0646605-A1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1995-04-05 | — | — | EP | disclosed |