Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761365 | 0.88 | LMNA (0.69) | KMT2ALMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6763979 | 0.86 | LMNA (0.56) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6762669 | 0.85 | TDP1 (0.58) | KMT2ALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL6767313 | 0.84 | KMT2A (0.68) | KMT2ALMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6759838 | 0.83 | KMT2A (0.50) | KMT2ALMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6766253 | 0.83 | TSHR (0.63) | KMT2ALMNASMN1; SMN2NPC1RAB9A | |
| Ethyl Benzoate SCHEMBL25388294 | 0.82 | LMNA (0.70) | KMT2ALMNAALDH1A1SMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL55674 | 0.82 | LMNA (0.70) | KMT2ALMNAALDH1A1SMN1; SMN2GAA | |
| Ethyl Benzoate SCHEMBL2762273 | 0.82 | LMNA (0.70) | KMT2ALMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6761495 | 0.81 | LMNA (0.63) | KMT2ALMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | VALENZUELA CORTES CARMEN MARIA (CL) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | PDE3A, PDE3B, PDE12 | KMT2A 2816/4885LMNA 1504/4885ALDH1A1 1744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.