Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18383703 | 0.85 | TSHR (0.66) | TSHRSLC6A3MAPTSMN1; SMN2LMNA | |
| SCHEMBL6764011 | 0.84 | MAPT (0.55) | TSHRSLC6A3MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL15673442 | 0.84 | SMN1; SMN2 (0.55) | TSHRSLC6A3MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6764009 | 0.83 | KMT2A (0.54) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL18389669 | 0.81 | MAPT (0.48) | TSHRSLC6A3MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27893218 | 0.81 | TSHR (0.59) | TSHRSLC6A3MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6763231 | 0.80 | SLC6A3 (0.61) | TSHRSLC6A3MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6761365 | 0.80 | LMNA (0.69) | TSHRSLC6A3MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL15673352 | 0.80 | TPMT (0.56) | TSHRSLC6A3MAPTKMT2ASMN1; SMN2 | |
| Methyl Benzoate SCHEMBL1332323 | 0.80 | TSHR (1.00) | TSHRSLC6A3MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | VALENZUELA CORTES CARMEN MARIA (CL) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | PDE3A, PDE3B, PDE12 | TSHR 4615/4885SLC6A3 414/4885MAPT 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.