Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | CCR1 | P32246 | 4/20 | 0.46 |
| ▸ | CCR8 | P51685 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CCR5 | P51681 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765967 | 0.84 | LMNA (0.48) | LMNACCR1CCR8KDM4ECCR5 | |
| SCHEMBL6763506 | 0.78 | LMNA (0.50) | LMNACCR1CCR8KDM4ECCR5 | |
| Phenanthroline SCHEMBL4576856 | 0.70 | LMNA (0.57) | LMNACCR1CCR8KDM4ECCR5 | |
| Phenanthroline SCHEMBL4577706 | 0.70 | LMNA (0.52) | LMNACCR1CCR8KDM4ECCR5 | |
| Phenanthroline SCHEMBL5726130 | 0.69 | CCR1 (0.50) | LMNACCR1CCR8KDM4ECCR5 | |
| Phenanthroline SCHEMBL29354015 | 0.68 | CCR1 (1.00) | LMNACCR1CCR8KDM4ECCR5 | |
| Phenanthroline SCHEMBL29367277 | 0.68 | CCR1 (1.00) | LMNACCR1CCR8KDM4ECCR5 | |
| Phenanthroline SCHEMBL8312 | 0.68 | CCR1 (1.00) | LMNACCR1CCR8KDM4ECCR5 | |
| Phenanthroline SCHEMBL8845760 | 0.68 | CCR1 (1.00) | LMNACCR1CCR8KDM4ECCR5 | |
| SCHEMBL2084343 | 0.67 | KDM4E (0.36) | KDM4EHTTHSD17B10ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730788-B1 | COUPLING WITH KETONE IN PRESENCE OF LANTHANIDE II METAL COMPOUND | UNIVERSITY OF NOTRE DAME | 2004-05-04 | — | — | US | disclosed |