SCHEMBL676426

SCHEMBL676426

Oc1cc(O)cc(C=Cc2c(O)cccc2O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 4/20 1.00
LCK P06239 3/20 0.63
PTGS1 P23219 5/20 0.56
KDM4E B2RXH2 3/20 0.56
MEN1 O00255 3/20 0.56
ALDH1A1 P00352 3/20 0.56
LMNA P02545 3/20 0.56
TP53 P04637 3/20 0.56
CYP1A2 P05177 3/20 0.56
CYP3A4 P08684 3/20 0.56
MAPT P10636 3/20 0.56
CYP2C9 P11712 3/20 0.56
HPGD P15428 3/20 0.56
KMT2A Q03164 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
HIF1A Q16665 3/20 0.56
HSD17B10 Q99714 3/20 0.56
ALOX5 P09917 3/20 0.56
APP P05067 3/20 0.56
CA12 O43570 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL676425 1.00 TTR (1.00) TTRLCKPTGS1KDM4EMEN1
SCHEMBL5003674 0.80 TTR (0.67) TTRLCKPTGS1KDM4EMEN1
SCHEMBL14128530 0.80 TTR (0.67) TTRLCKPTGS1KDM4EMEN1
SCHEMBL720795 0.78 LCK (1.00) TTRLCKPTGS1KDM4EMEN1
SCHEMBL720794 0.78 LCK (1.00) TTRLCKPTGS1KDM4EMEN1
SCHEMBL28285006 0.78 TTR (0.63) TTRLCKPTGS1KDM4EMEN1
SCHEMBL23754269 0.77 LCK (1.00) TTRLCKPTGS1KDM4EMEN1
SCHEMBL1425963 0.77 TTR (0.63) TTRPTGS1MAPTALOX5MAOB
SCHEMBL30194225 0.77 LCK (1.00) TTRLCKPTGS1KDM4EMEN1
SCHEMBL23754267 0.77 LCK (1.00) TTRLCKPTGS1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12514929-B2 Deformable nano-scale vehicles (DNVS) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-06 US claimed
CN-116270564-A Application of 4,3',5' -trihydroxy resveratrol compound in preparation of coronavirus 3CL protease inhibitor 陕西科技大学 2023-06-23 CN claimed
US-20200030457-A1 DEFORMABLE NANO-SCALE VEHICLES (DNVS) FOR TRANS-BLOOD BRAIN BARRIER, TRANS-MUCOSAL, AND TRANSDERMAL DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-01-30 US claimed
CN-110662532-A Deformable Nanoscale Vehicles (DNVS) for cross-blood brain barrier, transmucosal and transdermal drug delivery 加利福尼亚大学董事会 2020-01-07 CN claimed
US-20100204339-A1 Orally Bioavailable Stilbenoids- Compositions and Therapeutic Applications Thereof SAMI LABS LTD (IN) 2010-08-12 US claimed
US-12514929-B2 Deformable nano-scale vehicles (DNVS) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-06 US disclosed
CN-116270564-B Application of 4,3',5' -trihydroxy resveratrol compound in preparation of coronavirus 3CL protease inhibitor 陕西科技大学 2025-07-18 CN disclosed
CN-118384138-A Application of Gnetol and its derivatives in preparing protein phosphatase PPM1B inhibitor and antiaging medicine 山东大学 2024-07-26 CN disclosed
CN-116270564-A Application of 4,3',5' -trihydroxy resveratrol compound in preparation of coronavirus 3CL protease inhibitor 陕西科技大学 2023-06-23 CN disclosed
CN-116270564-A Application of 4,3',5' -trihydroxy resveratrol compound in preparation of coronavirus 3CL protease inhibitor 陕西科技大学 2023-06-23 CN disclosed
US-20200030457-A1 DEFORMABLE NANO-SCALE VEHICLES (DNVS) FOR TRANS-BLOOD BRAIN BARRIER, TRANS-MUCOSAL, AND TRANSDERMAL DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-01-30 US disclosed
CN-110662532-A Deformable Nanoscale Vehicles (DNVS) for cross-blood brain barrier, transmucosal and transdermal drug delivery 加利福尼亚大学董事会 2020-01-07 CN disclosed
US-20120207809-A1 Method and system for effecting changes in pigmented tissue MOAZED KAMBIZ THOMAS (US) 2012-08-16 US disclosed
US-20120076848-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2012-03-29 US disclosed
US-20110280909-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2011-11-17 US disclosed
WO-2011011065-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2011-01-27 WO disclosed
US-20100204340-A1 ORALLY BIOAVAILABLE STILBENOIDS- COMPOSITIONS AND THERAPEUTIC APPLICATIONS THEREOF SAMI LABS LIMITED (IN) 2010-08-12 US disclosed
US-20100204340-A1 ORALLY BIOAVAILABLE STILBENOIDS- COMPOSITIONS AND THERAPEUTIC APPLICATIONS THEREOF SAMI LABS LIMITED (IN) 2010-08-12 US disclosed
US-20100204339-A1 Orally Bioavailable Stilbenoids- Compositions and Therapeutic Applications Thereof SAMI LABS LTD (IN) 2010-08-12 US disclosed
WO-2010087983-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2010-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204340-A1 ORALLY BIOAVAILABLE STILBENOIDS- COMPOSITIONS AND THERAPEUTIC APPLICATIONS THEREOF SIRT1, SIRT3, LRBA TTR 3502/4885LCK 4518/4885PTGS1 1943/4885
US-20100204339-A1 Orally Bioavailable Stilbenoids- Compositions and Therapeutic Applications Thereof SIRT1, SIRT2, SIRT3 TTR 4522/4885LCK 4613/4885PTGS1 1716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.