SCHEMBL720795

SCHEMBL720795

Oc1cc(O)cc(C=Cc2cc(O)cc(O)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 3/20 1.00
PTGS1 P23219 7/20 0.74
TTR P02766 5/20 0.74
KDM4E B2RXH2 4/20 0.74
LMNA P02545 4/20 0.74
MEN1 O00255 3/20 0.74
ALDH1A1 P00352 3/20 0.74
TP53 P04637 3/20 0.74
CYP1A2 P05177 3/20 0.74
CYP3A4 P08684 3/20 0.74
MAPT P10636 3/20 0.74
CYP2C9 P11712 3/20 0.74
HPGD P15428 3/20 0.74
KMT2A Q03164 3/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
HIF1A Q16665 3/20 0.74
HSD17B10 Q99714 3/20 0.74
ALOX5 P09917 3/20 0.74
CYP1A1 P04798 3/20 0.74
CYP1B1 Q16678 3/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL720794 1.00 LCK (1.00) LCKPTGS1TTRKDM4ELMNA
Resveratrol SCHEMBL19425 0.86 PTGS1 (1.00) LCKPTGS1TTRKDM4ELMNA
SCHEMBL1393726 0.86 LCK (0.74) LCKPTGS1TTRKDM4ELMNA
Resveratrol SCHEMBL17629801 0.86 PTGS1 (1.00) LCKPTGS1TTRKDM4ELMNA
SCHEMBL1393728 0.86 LCK (0.74) LCKPTGS1TTRKDM4ELMNA
Resveratrol SCHEMBL19426 0.86 PTGS1 (1.00) LCKPTGS1TTRKDM4ELMNA
Resveratrol SCHEMBL3704258 0.86 PTGS1 (1.00) LCKPTGS1TTRKDM4ELMNA
Cis-Resveratrol SCHEMBL1931746 0.86 PTGS1 (1.00) LCKPTGS1TTRKDM4ELMNA
Resveratrol SCHEMBL20164915 0.86 PTGS1 (1.00) LCKPTGS1TTRKDM4ELMNA
Resveratrol SCHEMBL2300985 0.86 PTGS1 (1.00) LCKPTGS1TTRKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313010-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 Szekeres, Thomas (AT) 2024-02-07 EP claimed
WO-2022200086-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 SZEKERES THOMAS (AT) 2022-09-29 WO claimed
US-10723834-B1 Low melting and low viscosity thermoset matrix resins from the Z configuration of polyhydroxy stilbenes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2020-07-28 US claimed
US-9187591-B1 Polyphenols and high-performance resins from syringaldehyde THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-11-17 US claimed
US-9127115-B1 Polyphenols and high-performance resins from syringaldehyde THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-09-08 US claimed
US-9051414-B1 Polyphenols and high-performance resins from syringaldehyde The United States of America as Represented by the Secretary of he Navy (US) 2015-06-09 US claimed
US-9018314-B1 Polyphenols and high-performance resins from syringaldehyde THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-04-28 US claimed
US-8993688-B1 Polyphenols and high-performance resins from syringaldehyde THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-03-31 US claimed
US-8993689-B1 Polyphenols and high-performance resins from syringaldehyde THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-03-31 US claimed
US-20110105633-A1 FUNCTIONALIZED STILBENE-POLYALKYLENE OXIDE PREPOLYMERS PROMETHEAN SURGICAL DEVICES LLC (US) 2011-05-05 US claimed
WO-2011049680-A1 CRYOSENSITIZING AGENTS FOR ENHANCEMENT OF CRYOABLATION BAUST JOHN M (US) 2011-04-28 WO claimed
EP-1654210-B1 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2008-07-30 EP claimed
US-20070191627-A1 Stilbene derivatives and their use in medicaments SZEKERES THOMAS 2007-08-16 US claimed
WO-2005102298-A1 MEDICAL SUBSTANCE MIXTURES CONTAINING RESVERATROL OR RESVERATROL-DERIVATIVES, IN ADDITION TO THE USE THEREOF IN THE PRODUCTION OF MEDICAMENTS SZEKERES THOMAS (AT) 2005-11-03 WO claimed
US-6414038-B2 A FORMULATION FOR REDUCING/PREVENTING GLYCATION OF PROTEINS OF SKIN AND/OR NAILS CONSISTS OF 3,3,5,5-TETRAHYDROXYSTILBENE COMPOUND OR O-ALKY OR O-ACYCL DERIVATIVES SOCIETE L'OREAL (FR) 2002-07-02 US claimed
US-20020028852-A1 Resveratrol analogs for prevention of disease RUTGERS, THE STATE UNIVERSITY 2002-03-07 US claimed
US-20010025056-A1 Hydroxystilbenes for reducing/inhibiting protein glycation and combating skin aging SOCIETE L'OREAL S.A. (FR) 2001-09-27 US claimed
EP-1110539-A1 Use of 3,3',5,5'-tetrahehydroxystilbene as a glycation inhibitor L'OREAL (FR) 2001-06-27 EP claimed
EP-4313010-B1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 SZEKERES THOMAS (AT) 2025-02-19 EP disclosed
US-4118559-A CNS AGENTS, ANALGESICS, TRANQUILIZERS PFIZER INC. (US) 1978-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010025056-A1 Hydroxystilbenes for reducing/inhibiting protein glycation and combating skin aging AGER, HMOX1, HAAO LCK 1275/4885PTGS1 431/4885TTR 115/4885
US-20070191627-A1 Stilbene derivatives and their use in medicaments PTGS2, PTGS1, PTGER2 LCK 3040/4885PTGS1 2/4885TTR 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.