Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764465 | 1.00 | ALDH1A1 (0.44) | ALDH1A1PARP1MAPK1GPR183CHRNA7 | |
| SCHEMBL6764426 | 0.95 | ALDH1A1 (0.47) | ALDH1A1PARP1MAPK1GPR183ACHE | |
| SCHEMBL6764421 | 0.95 | ALDH1A1 (0.47) | ALDH1A1PARP1MAPK1GPR183ACHE | |
| SCHEMBL6764113 | 0.92 | ALDH1A1 (0.42) | ALDH1A1KMT2A | |
| SCHEMBL6764116 | 0.92 | ALDH1A1 (0.42) | ALDH1A1KMT2A | |
| SCHEMBL6757349 | 0.88 | GPR183 (0.42) | GPR183CHRNA7MTNR1BNPC1KMT2A | |
| SCHEMBL6757351 | 0.88 | GPR183 (0.42) | GPR183CHRNA7MTNR1BNPC1KMT2A | |
| SCHEMBL6761603 | 0.87 | GPR183 (0.42) | GPR183CHRNA7MTNR1BNPC1KMT2A | |
| SCHEMBL6761601 | 0.87 | GPR183 (0.42) | GPR183CHRNA7MTNR1BNPC1KMT2A | |
| SCHEMBL6759793 | 0.86 | GPR183 (0.45) | ALDH1A1GPR183CHRNA7MTNR1BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106635-A1 | having small-conductance potassium channel (SK) blocking activity | TANABE SEIYAKU CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106635-A1 | having small-conductance potassium channel (SK) blocking activity | KCNN1, KCNN2, KCNN3 | ALDH1A1 1229/4885PARP1 3384/4885MAPK1 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.