Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | PRKCA | P17252 | 4/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165596 | 0.83 | MAPT (0.47) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL6765097 | 0.74 | MAPT (0.55) | MAPTLMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL9063089 | 0.73 | EPHX1 (0.44) | ALDH1A1 | |
| SCHEMBL6988966 | 0.73 | EPHX1 (0.47) | ALDH1A1 | |
| SCHEMBL1868926 | 0.73 | EPHX1 (0.47) | ALDH1A1 | |
| SCHEMBL10593737 | 0.73 | MAPT (0.62) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL15589935 | 0.73 | EPHX1 (0.47) | ALDH1A1 | |
| SCHEMBL27756824 | 0.72 | EPHX1 (0.50) | MAPK1ALDH1A1 | |
| SCHEMBL6578955 | 0.71 | DGKA (0.54) | MAPTLMNAALDH1A1DGKA | |
| SCHEMBL10592200 | 0.71 | MAPT (0.66) | MAPTMAPK1LMNAPRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |