Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ATIC | P31939 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6766536 | 0.90 | HDAC1 (0.52) | MGAT2LMNAKDM1AGPR27AR | |
| SCHEMBL6571783 | 0.85 | LMNA (0.51) | MGAT2LMNAPOLBKDM1ARORC | |
| SCHEMBL6762133 | 0.84 | POLB (0.53) | LMNAPOLBKDM1AARRORC | |
| SCHEMBL24254519 | 0.83 | MGAT2 (0.57) | MGAT2LMNAPOLBGPR27HDAC1 | |
| SCHEMBL6569935 | 0.83 | MCL1 (0.49) | LMNAPOLBKDM1ARORCHDAC1 | |
| SCHEMBL6571948 | 0.83 | HDAC1 (0.48) | LMNAPOLBKDM1AGPR27AR | |
| SCHEMBL6762119 | 0.83 | TMPRSS6 (0.57) | MGAT2LMNAPOLBHDAC1HDAC8 | |
| SCHEMBL24254503 | 0.82 | MGAT2 (0.54) | MGAT2LMNAGPR27ALDH1A1 | |
| SCHEMBL6574016 | 0.81 | HDAC1 (0.51) | LMNAKDM1AGPR27ARRORC | |
| SCHEMBL6574325 | 0.80 | LMNA (0.44) | LMNAKDM1ARORCHPGDBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | NAT1, CYP3A5, CYP3A7 | MGAT2 566/4885LMNA 1447/4885POLB 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.