Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 6/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492246 | 0.76 | AHR (0.44) | ALDH1A1KDM4EKIF11AHRHSD17B10 | |
| SCHEMBL29563297 | 0.75 | ALDH1A1 (0.72) | ALDH1A1KDM4EGLAGAAHTT | |
| SCHEMBL29643229 | 0.75 | ALDH1A1 (0.72) | ALDH1A1KDM4EGLAGAAHTT | |
| SCHEMBL6976558 | 0.75 | ALDH1A1 (0.72) | ALDH1A1KDM4EGLAGAAHTT | |
| SCHEMBL6484779 | 0.73 | KIF11 (0.49) | ALDH1A1KDM4EKIF11AHRHSD17B10 | |
| SCHEMBL869228 | 0.71 | KIF11 (0.59) | ALDH1A1KDM4EKIF11AHRHSD17B10 | |
| SCHEMBL28363827 | 0.69 | AHR (0.59) | ALDH1A1KDM4EGLAGAAHTT | |
| SCHEMBL29562978 | 0.69 | AHR (0.64) | ALDH1A1KDM4EGLAGAAHTT | |
| SCHEMBL6756610 | 0.69 | AHR (0.64) | ALDH1A1KDM4EGLAGAAHTT | |
| SCHEMBL13010630 | 0.68 | KIF11 (0.79) | ALDH1A1KDM4EGAAKIF11AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800656-B2 | Tricyclic compounds and method of treating herpes virus | WARNER LAMBERT COMPANY | 2004-10-05 | — | — | US | disclosed |