Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 7/20 | 0.62 |
| ▸ | STAT6 | P42226 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TYMP | P19971 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | THPO | P40225 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27732293 | 0.88 | TYMP (0.73) | SLC29A1STAT6ADORA3TP53TDP1 | |
| SCHEMBL7615673 | 0.88 | TYMP (0.73) | SLC29A1STAT6ADORA3TP53TDP1 | |
| SCHEMBL5983454 | 0.88 | TYMP (0.73) | SLC29A1STAT6ADORA3TP53TDP1 | |
| SCHEMBL28310224 | 0.83 | SLC29A1 (0.55) | SLC29A1STAT6ADORA3TP53ADORA1 | |
| SCHEMBL28660199 | 0.80 | DPP4 (0.54) | SLC29A1STAT6ADORA3TP53ADORA1 | |
| SCHEMBL23666509 | 0.79 | DPP4 (0.60) | SLC29A1STAT6ADORA3TP53ADORA1 | |
| SCHEMBL21114408 | 0.79 | DPP4 (0.60) | SLC29A1STAT6ADORA3TP53ADORA1 | |
| SCHEMBL18512841 | 0.79 | DPP4 (0.60) | SLC29A1STAT6ADORA3TP53ADORA1 | |
| SCHEMBL19553541 | 0.79 | DPP4 (0.60) | SLC29A1STAT6ADORA3TP53ADORA1 | |
| SCHEMBL22413038 | 0.79 | ADORA2A (0.58) | SLC29A1STAT6ADORA3ADORA1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110718-A1 | Anti-HCV nucleoside derivatives | DEVOS RENE (GB) | 2004-06-10 | — | — | US | claimed |
| CN-1466591-A | Nucleoside derivatives | - | 2004-01-07 | — | — | CN | claimed |
| US-20030008841-A1 | Anti-HCV nucleoside derivatives | F. HOFFMAN-LA ROCHE, A SWISS COMPANY (CH) | 2003-01-09 | — | — | US | claimed |
| CN-101184495-B | Methods, compositions, and formulations for preventing or reducing adverse effects in a patient | PERICOR THERAPEUTICS INC | 2011-09-14 | — | — | CN | disclosed |
| CN-101184495-A | Methods, compositions, and formulations for preventing or reducing adverse effects in a patient | PERICOR THERAPEUTICS INC (US) | 2008-05-21 | — | — | CN | disclosed |
| US-20040110718-A1 | Anti-HCV nucleoside derivatives | DEVOS RENE (GB) | 2004-06-10 | — | — | US | disclosed |
| CN-1466591-A | Nucleoside derivatives | - | 2004-01-07 | — | — | CN | disclosed |
| US-20030008841-A1 | Anti-HCV nucleoside derivatives | F. HOFFMAN-LA ROCHE, A SWISS COMPANY (CH) | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008841-A1 | Anti-HCV nucleoside derivatives | PNP, HAVCR2, NUDT14 | SLC29A1 18/4885STAT6 1423/4885ADORA3 102/4885 |
| US-20040110718-A1 | Anti-HCV nucleoside derivatives | PNP, HAVCR2, NUDT14 | SLC29A1 18/4885STAT6 1423/4885ADORA3 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.