SCHEMBL6765776

SCHEMBL6765776

Nc1cc(C(=C(c2ccccc2)S(=O)(=O)O)S(=O)(=O)O)c(N)c(N)c1N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
THRB P10828 1/20 0.36
PKM P14618 1/20 0.36
MCL1 Q07820 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 3/20 0.35
GRK6 P43250 1/20 0.33
ALDH1A1 P00352 1/20 0.32
PBRM1 Q86U86 1/20 0.32
IDO1 P14902 1/20 0.32
AKR1C3 P42330 1/20 0.31
TSHR P16473 3/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1719171 0.80 MAPT (0.53) MAPTGAAMAPK1KMT2AKDM4E
SCHEMBL38676 0.79 MAPT (0.44) MAPTGAAMAPK1KMT2AKDM4E
SCHEMBL3906463 0.77 ALDH1A1 (0.39) MAPTGAAMEN1KMT2AKDM4E
SCHEMBL285311 0.76 TSHR (0.48) MAPTMAPK1MEN1KMT2AKDM4E
Ammonia Solution, Strong SCHEMBL1411437 0.74 TSHR (0.46) MAPTMAPK1MEN1KMT2AKDM4E
SCHEMBL28740968 0.74 TSHR (0.46) MAPTMAPK1MEN1KMT2AKDM4E
SCHEMBL686613 0.74 MAPT (0.60) MAPTGAAMAPK1MEN1KMT2A
SCHEMBL19253345 0.73 MAPT (0.39) MAPTGAAMAPK1MEN1KMT2A
SCHEMBL4056356 0.73
Hydrochloric Acid SCHEMBL5169493 0.73 MAPT (0.58) MAPTGAAMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2215167-B1 USE OF ZERO-ORDER DIFFRACTIVE PIGMENTS BASF SE (DE) 2014-09-24 EP disclosed
EP-2376581-B1 INTERFERENCE PIGMENTS ON THE BASIS OF PERLITE FLAKES BASF SE (DE) 2013-07-03 EP disclosed
US-20040109831-A1 Cosmetic compositions for the protection and optical enhancement of tattooed skin M & M INX CO. 2004-06-10 US disclosed