SCHEMBL19253345

SCHEMBL19253345

Nc1cc(C(=C(c2ccccc2)c2ccccc2)c2ccccc2)c(N)c(N)c1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.39
GAA P10253 1/20 0.39
POLB P06746 2/20 0.38
MAPK1 P28482 3/20 0.35
KMT2A Q03164 2/20 0.35
PKM P14618 2/20 0.35
GFER P55789 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
THRB P10828 1/20 0.35
MCL1 Q07820 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PBRM1 Q86U86 1/20 0.34
IDO1 P14902 1/20 0.34
HSP90AA1 P07900 1/20 0.34
NTSR1 P30989 1/20 0.34
TSHR P16473 2/20 0.33
F2 P00734 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686613 0.80 MAPT (0.60) MAPTGAAPOLBMAPK1KMT2A
Hydrochloric Acid SCHEMBL5169493 0.79 MAPT (0.58) MAPTGAAPOLBMAPK1KMT2A
SCHEMBL28587223 0.79 CES2 (0.52) MAPTGAAPOLBMAPK1KMT2A
SCHEMBL27955730 0.76 MAPT (0.59) MAPTGAAPOLBMAPK1KMT2A
SCHEMBL1286400 0.75 MAPT (0.48) MAPTGAAPOLBMAPK1KMT2A
SCHEMBL19253245 0.75 MAPT (0.36) MAPTGAAPOLBMAPK1KMT2A
SCHEMBL6765776 0.73 MAPT (0.36) MAPTGAAPOLBMAPK1KMT2A
SCHEMBL67982 0.71 CES1 (0.53) MAPTPOLBMAPK1KMT2APKM
Benzene SCHEMBL28326432 0.71 CES1 (0.53) MAPTPOLBMAPK1KMT2APKM
SCHEMBL2688381 0.69 KDM4E (0.48) MAPTGAAPOLBMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221895-A Two-dimensional covalent organic framework material containing crown ether group, and preparation method and application thereof 中国科学院兰州化学物理研究所 2024-06-21 CN claimed
CN-113637185-B Preparation of hydrogel and information encryption and decryption method and application 湖南工业大学 2022-10-21 CN claimed
CN-113637185-A Preparation of hydrogel and information encryption and decryption method and application 湖南工业大学 2021-11-12 CN claimed
US-20250026889-A1 TWO DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS U.S. GOVERNMENT, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2025-01-23 US disclosed
US-12110367-B2 Two-dimensional polymers comprised of a combination of stiff and compliant molecular units THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2024-10-08 US disclosed
CN-113637185-B Preparation of hydrogel and information encryption and decryption method and application 湖南工业大学 2022-10-21 CN disclosed
CN-113637185-A Preparation of hydrogel and information encryption and decryption method and application 湖南工业大学 2021-11-12 CN disclosed
US-20200148827-A1 TWO-DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2020-05-14 US disclosed
US-10590241-B2 Two-dimensional polymers comprised of a combination of stiff and compliant molecular units THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2020-03-17 US disclosed
US-20170240706-A1 TWO-DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS ARMY, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2017-08-24 US disclosed