Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15042239 | 0.81 | CHRM2 (0.41) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL246324 | 0.81 | CHRM2 (0.41) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL253506 | 0.81 | CHRM2 (0.41) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL27690833 | 0.77 | OPRM1 (0.53) | CHRM2CHRM1CYP2D6ALDH1A1LMNA | |
| SCHEMBL10077960 | 0.76 | ALDH1A1 (0.59) | SMN1; SMN2CYP2D6HPGDALDH1A1LMNA | |
| SCHEMBL254709 | 0.76 | CCR1 (0.40) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL153570 | 0.75 | CHRM2 (0.39) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL253862 | 0.75 | CHRM2 (0.39) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18731070 | 0.75 | CHRM2 (0.39) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL24872725 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434573-A2 | IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN AND INFLAMMATION | Omeros Corporation (US) | 2004-07-07 | — | — | EP | claimed |
| US-20020028798-A1 | Irrigation solution and method for inhibition of pain and inflammation | OMEROS MEDICAL SYSTEMS | 2002-03-07 | — | — | US | claimed |
| WO-2000023062-A2 | IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN AND INFLAMMATION | OMEROS MEDICAL SYSTEMS, INC. (US) | 2000-04-27 | — | — | WO | claimed |
| US-20220062252-A1 | CYCLOOXYGENASE INHIBITOR AND CALCIUM CHANNEL ANTAGONIST COMPOSITIONS AND METHODS FOR USE IN UROLOGICAL PROCEDURES | OMEROS CORP (US) | 2022-03-03 | — | — | US | disclosed |
| US-20210290605-A1 | CYCLOOXYGENASE INHIBITOR AND CALCIUM CHANNEL ANTAGONIST COMPOSITIONS AND METHODS FOR USE IN UROLOGICAL PROCEDURES | OMEROS CORP (US) | 2021-09-23 | — | — | US | disclosed |
| US-20190083477-A1 | Cyclooxygenase Inhibitor and Calcium Channel Antagonist Compositions and Methods for Use in Urological Procedures | OMEROS CORP (US) | 2019-03-21 | — | — | US | disclosed |
| US-9855256-B2 | Cyclooxygenase inhibitor and calcium channel antagonist compositions and methods for use in urological procedures | OMEROS CORPORATION (US) | 2018-01-02 | — | — | US | disclosed |
| US-20170246150-A1 | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation | OMEROS CORPORATION | 2017-08-31 | — | — | US | disclosed |
| US-20170182007-A1 | Arthroscopic Irrigation Solution and Method for Peripheral Vasoconstriction and Inhibition of Pain and Inflammation | OMEROS CORPORATION | 2017-06-29 | — | — | US | disclosed |
| EP-1881821-B1 | COMPOSITIONS COMPRISING KETOPROFEN AND CALCIUM CHANNEL ANTAGONIST FOR USE IN UROLOGICAL PROCEDURES | OMEROS CORP (US) | 2016-11-09 | — | — | EP | disclosed |
| US-20160184272-A1 | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation | OMEROS CORPORATION | 2016-06-30 | — | — | US | disclosed |
| US-20060229588-A1 | Irrigation solution and method for inhibition of pain and inflammation | OMEROS CORPORATION | 2006-10-12 | — | — | US | disclosed |
| US-20060205658-A1 | Irrigation solution and method for inhibition of pain and inflammation | OMEROS CORPORATION | 2006-09-14 | — | — | US | disclosed |
| US-20060205657-A1 | Irrigation solution and method for inhibition of pain and inflammation | OMEROS CORPORATION | 2006-09-14 | — | — | US | disclosed |
| US-7091181-B2 | Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors | OMEROS CORPORATION (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1434573-A2 | IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN AND INFLAMMATION | Omeros Corporation (US) | 2004-07-07 | — | — | EP | disclosed |
| US-20030096807-A1 | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation | OMEROS CORPORATION | 2003-05-22 | — | — | US | disclosed |
| US-20030087962-A1 | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation | OMEROS CORPORATION | 2003-05-08 | — | — | US | disclosed |
| US-20020028798-A1 | Irrigation solution and method for inhibition of pain and inflammation | OMEROS MEDICAL SYSTEMS | 2002-03-07 | — | — | US | disclosed |
| WO-2000023062-A2 | IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN AND INFLAMMATION | OMEROS MEDICAL SYSTEMS, INC. (US) | 2000-04-27 | — | — | WO | disclosed |