Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PDE9A | O76083 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BCL6 | P41182 | 2/20 | 0.41 |
| ▸ | BCOR | Q6W2J9 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924452 | 0.87 | GRIK1 (0.54) | TLR8TLR7KDM4EMAPTMAPK1 | |
| SCHEMBL6763618 | 0.81 | HSP90AA1 (0.51) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20772686 | 0.81 | PLAU (0.51) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL1119917 | 0.79 | MAPT (0.57) | MEN1KMT2ASMYD3KDM4EMAPT | |
| SCHEMBL6763785 | 0.79 | HPGD (0.50) | MEN1KMT2ASMYD3KDM4EMAPT | |
| SCHEMBL1095502 | 0.77 | SIRT2 (0.69) | MEN1KMT2ASMYD3KDM4EMAPT | |
| SCHEMBL4434572 | 0.76 | CA12 (0.43) | TLR8TLR7SMYD3MAPK1PDE9A | |
| SCHEMBL29511878 | 0.76 | BCL6 (0.60) | MEN1KMT2ASMYD3KDM4EMAPT | |
| SCHEMBL4422966 | 0.76 | BCL6 (0.60) | MEN1KMT2ASMYD3KDM4EMAPT | |
| SCHEMBL28431190 | 0.76 | MAPT (0.49) | MEN1KMT2ASMYD3KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |