Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763618 | 0.88 | HSP90AA1 (0.51) | HPGDSMN1; SMN2POLBMLYCDALDH1A1 | |
| SCHEMBL6766299 | 0.79 | MEN1 (0.46) | HPGDSMN1; SMN2POLBALDH1A1LMNA | |
| SCHEMBL6763737 | 0.76 | MAPT (0.50) | HPGDSMN1; SMN2POLBALDH1A1RXFP1 | |
| SCHEMBL9694832 | 0.76 | MLYCD (0.72) | HPGDSMN1; SMN2MLYCDALDH1A1LMNA | |
| SCHEMBL6766834 | 0.76 | MAPT (0.46) | HPGDSMN1; SMN2POLBALDH1A1LMNA | |
| SCHEMBL13062695 | 0.74 | MEN1 (0.47) | ALDH1A1LMNAMAPTGAAKDM4E | |
| SCHEMBL9361376 | 0.73 | TP53 (0.60) | HPGDSMN1; SMN2MLYCDALDH1A1LMNA | |
| SCHEMBL1119917 | 0.73 | MAPT (0.57) | ALDH1A1LMNATP53MAPTGAA | |
| SCHEMBL6766391 | 0.73 | KDM4E (0.59) | SMN1; SMN2POLBALDH1A1LMNARXFP1 | |
| SCHEMBL6767714 | 0.73 | ALDH1A1 (0.53) | HPGDPOLBALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |