Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767882 | 0.83 | GAA (0.54) | GAAPKMALDH1A1MAPTHSD17B10 | |
| SCHEMBL6768119 | 0.83 | GAA (0.54) | GAAPKMPDE3BPDE3AP2RY12 | |
| SCHEMBL5393113 | 0.81 | GAA (0.59) | GAAPKMALDH1A1MAPTGRIN2D | |
| SCHEMBL13303940 | 0.80 | GAA (0.68) | GAAPKMPDE3BPDE3AALDH1A1 | |
| SCHEMBL6767005 | 0.77 | GAA (0.51) | GAAPKMALDH1A1MAPTHSD17B10 | |
| SCHEMBL2056376 | 0.77 | GAA (0.63) | GAAPKMPDE3BPDE3AALDH1A1 | |
| SCHEMBL1824734 | 0.77 | GAA (0.54) | GAAPKMALDH1A1MAPTGRIN2D | |
| SCHEMBL6767362 | 0.76 | PDE3B (0.65) | GAAPKMPDE3BPDE3AP2RY12 | |
| SCHEMBL13015140 | 0.75 | GAA (0.53) | GAAPKMALDH1A1GRIN2DGRIN3B | |
| SCHEMBL28619121 | 0.75 | GAA (0.53) | GAAPKMPDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |