Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.65 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.65 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BCL6 | P41182 | 1/20 | 0.44 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767607 | 0.85 | PDE3B (0.54) | PDE3BPDE3AP2RY12MAPTGAA | |
| SCHEMBL6763567 | 0.85 | SMN1; SMN2 (0.54) | PDE3BPDE3AP2RY12MAPTGAA | |
| SCHEMBL6763763 | 0.82 | GAA (0.54) | PDE3BPDE3AP2RY12MAPTGAA | |
| SCHEMBL6893722 | 0.79 | GAA (0.49) | PDE3BPDE3AP2RY12MAPTGAA | |
| SCHEMBL16720796 | 0.79 | ALOX15 (0.56) | PDE3BPDE3AP2RY12CYP4F2CYP4A11 | |
| SCHEMBL22057895 | 0.79 | PDE3B (0.51) | PDE3BPDE3AP2RY12CYP4F2CYP4A11 | |
| SCHEMBL31239037 | 0.79 | GAA (0.54) | PDE3BPDE3AP2RY12GAAPKM | |
| SCHEMBL68902 | 0.78 | CYP4F2 (0.85) | PDE3BPDE3AP2RY12CYP4F2CYP4A11 | |
| SCHEMBL6766390 | 0.77 | GAA (0.57) | PDE3BPDE3AP2RY12MAPTGAA | |
| SCHEMBL6772923 | 0.77 | GAA (0.49) | PDE3BPDE3AP2RY12MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |