Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27050920 | 0.89 | TSHR (0.44) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL24429198 | 0.86 | EPHX2 (0.44) | ALDH1A1 | |
| SCHEMBL27050825 | 0.86 | EPHX2 (0.44) | ALDH1A1 | |
| SCHEMBL31465144 | 0.86 | EPHX2 (0.44) | ALDH1A1 | |
| SCHEMBL18104358 | 0.86 | EPHX2 (0.44) | ALDH1A1 | |
| SCHEMBL27055720 | 0.85 | EPHX1 (0.44) | SMN1; SMN2 | |
| SCHEMBL27052622 | 0.85 | EPHX1 (0.44) | SMN1; SMN2 | |
| SCHEMBL27097854 | 0.85 | EPHX1 (0.44) | SMN1; SMN2 | |
| SCHEMBL714350 | 0.84 | MEN1 (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1687468 | 0.84 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004044141-A2 | CONJUGATED OLIGOMERIC COMPOUNDS AND THEIR USE IN GENE MODULATION | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-27 | — | — | WO | disclosed |
| EP-1112279-A4 | METHODS FOR THE PREPARATION OF CONJUGATED OLIGOMERS | ISIS PHARMACEUTICALS INC (US) | 2002-06-19 | — | — | EP | disclosed |
| EP-1112279-A1 | METHODS FOR THE PREPARATION OF CONJUGATED OLIGOMERS | ISIS PHARMACEUTICALS, INC. (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000014098-A1 | METHODS FOR THE PREPARATION OF CONJUGATED OLIGOMERS | ISIS PHARMACEUTICALS, INC. (US) | 2000-03-16 | — | — | WO | disclosed |